Epithelial-mesenchymal transition (EMT) of lung epithelial cells may lead to BPD. Objective To investigate the potential occurrence of EMT in a newborn rat model of BPD. Methods Newborn rats were exposed to a hyperoxic environment within 12hr of birth. Lung tissue and isolated alveolar ...
transition(EMT)microfluidicstumoroidsTumor microenvironment and the interplay of physical and mechanical forces are key determinants of cancer initiation, progression, and response to drug treatment. However, the impact of tumor microenvironment on cancer progression is poorly understood, in large due to ...
Epithelial–mesenchymal transition (EMT), via activation of Wnt signaling, is prevailing in embryogenesis, but postnatally it only occurs in pathological p... Tetsuya,Kawakita,Edgar,... - 《Journal of Cellular Physiology》 被引量: 49发表: 2012年 Epithelial‐to‐mesenchymal transitions in the liver...
Aberrant TGF-β signaling is common in human cancers and contributes to tumor metastasis by inducing an epithelial-mesenchymal transition (EMT). In previous studies, we demonstrated that SENP2 suppresses bladder cancer cell migration and invasion. However, little is known about whether SENP2 inhibits...
Zhang, LiangYuan, XiaoliangLü, ZhongOncology Research Featuring Preclinical and Clinical Cancer TherapeuticsWu, H.; Wang, X.; Mo, N.; Zhang, L.; Yuan, X.; Lu, Z. B7-homolog 4 promotes epithelial-mesenchymal transition and invasion of bladder cancer cells via activation of nuclear factor-...
On the contrary, forced expression of KDM5B leads to enhanced migration and invasion, accompanied by canonical alterations of epithelial–mesenchymal transition (EMT). Mechanism investigations demonstrated that KDM5B activates Wnt/β‐catenin pathway, and inhibition of Wnt/β‐catenin pathway via a ...
All‐trans retinoic acid reverses epithelial‐mesenchymal transition in paclitaxel‐resistant cells by inhibiting nuclear factor kappa B and upregulating gap junctions doi:10.1111/cas.13855Cancer ScienceShi, GuilingZheng, XiaoliWu, XiaojingWang, SiqiWang, YijiaXing, Fei...
This article has been presented as a preprint: Scorpion Venom Polypeptide Inhibits Pulmonary Epithelial-Mesenchymal Transition in Systemic Sclerosis-Interstitial Lung Disease Model Mice by Intervening TGF-β1/Smad Signaling Pathway. DOI: 10.21203/rs.3.rs-1238400/v1. Yan Zhang, Liping Xu are co-firs...
Downregulation of miR‐3127‐5p promotes epithelial‐mesenchymal transition via FZD4 regulation of Wnt/β‐catenin signaling in non‐small‐cell lung cancer doi:10.1002/mc.22805Molecular CarcinogenesisYang, YangSun, YifengWu, YunTang, DongfangDing, XiXu, WenSu, BoGao, Wen...
The Key Role of Epithelial to Mesenchymal Transition (EMT) in Hypertensive Kidney Disease epithelial to mesenchymal transition (EMT), hypertension, angiotensin II, endothelinAccumulating evidence indicates that epithelial-to-mesenchymal transition (EMT)... T Seccia,B Caroccia,M Piazza,... - 《...