Epithelial-mesenchymal transition (EMT) of lung epithelial cells may lead to BPD. Objective To investigate the potential occurrence of EMT in a newborn rat model of BPD. Methods Newborn rats were exposed to a hyperoxic environment within 12hr of birth. Lung tissue and isolated alveolar ...
(1994). Mesenchymal-epi- thelial transition. BioEssays 16, 305-307.BIRCHMEIER, W. and BIRCHMEIER, C. Mesenchymal-epithelial transitions. Bioessays., 16, 305-307 (1994b).Birchmeier, W., and Birchmeier, C. (1994): Mesenchymal-epithelial transitions. Bioessays 5:305-307....
2022年3月,辉骏生物的合作伙伴——中山大学中山眼科中心团队在期刊Advanced Science(IF2022=17.521)上发表题为“MYPT1/PP1-Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial-Mesenchymal Transition in Fibrosis through Control of Multiple Families of Genes “的文章。实验发现甲基转移酶EZH2在晶状体中高表达...
Epithelial–mesenchymal transition (EMT), via activation of Wnt signaling, is prevailing in embryogenesis, but postnatally it only occurs in pathological p... Tetsuya,Kawakita,Edgar,... - 《Journal of Cellular Physiology》 被引量: 49发表: 2012年 Epithelial‐to‐mesenchymal transitions in the liver...
Epithelial-mesenchymal transition EndMT: Endothelial-to-mesenchymal transition MSCs: Mesenchymal stem cells ER: Endoplasmic reticulum TGF-β1: Transforming growth factor-β1 UPR: Unfolded protein response NAFLD: Nonalcoholic fatty liver disease huMSCs: Human umbilical cord-derived mese...
Aberrant TGF-β signaling is common in human cancers and contributes to tumor metastasis by inducing an epithelial-mesenchymal transition (EMT). In previous studies, we demonstrated that SENP2 suppresses bladder cancer cell migration and invasion. However, little is known about whether SENP2 inhibits...
Nonluminal breast cancer has high early metastasis and treatment resistance, and neoadjuvant chemotherapy (NAC) is needed. The presence of cancer stem cells (CSC) and epithelial-mesenchymal transition (EMT) leads to poor prognosis. This study investigated the changes in CSC markers and EMT markers ...
TGFβ‐mediated RhoA expression is necessary for epithelial‐mesenchymal transition in the embryonic chick heart Developmental DynamicsAndré Luiz P. TavaresMelania E. Mercado‐PimentelRaymond B. RunyanGregory T. Kitten
Epithelial‐mesenchymal transition (EMT) is crucial for cancer invasion and metastasis. However, the mechanisms whereby large tumors tend to undergo EMT remain unclear. We conducted a subgenome‐wide screen and identified KLHL23 as an HCC invasion suppressor by inhibiting EMT. KLHL23 binds to ...
transition(EMT)microfluidicstumoroidsTumor microenvironment and the interplay of physical and mechanical forces are key determinants of cancer initiation, progression, and response to drug treatment. However, the impact of tumor microenvironment on cancer progression is poorly understood, in large due to ...