Epithelial-mesenchymal transition (EMT) of lung epithelial cells may lead to BPD. Objective To investigate the potential occurrence of EMT in a newborn rat model of BPD. Methods Newborn rats were exposed to a hyperoxic environment within 12hr of birth. Lung tissue and isolated alveolar ...
Epithelial-mesenchymal transitions (EMT) are vital for morphogenesis during embryonic development and are also implicated in the conversion of early stage tumors into invasive malignancies. Several key inducers of EMT are transcription factors that repress E-cadherin expression. A recent report in Cell(...
This investigation thus provides a basis for using this basic developmental biology phenomenon mesenchymal to epithelial transition as a strategy to generate a large number of functional islets from stem cells of mesenchymal origin. J. Cell. Biochem. 2013 Wiley Periodicals, Inc. 展开 ...
2022年3月,辉骏生物的合作伙伴——中山大学中山眼科中心团队在期刊Advanced Science(IF2022=17.521)上发表题为“MYPT1/PP1-Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial-Mesenchymal Transition in Fibrosis through Control of Multiple Families of Genes “的文章。实验发现甲基转移酶EZH2在晶状体中高表达...
epithelial‐mesenchymal transitionnanomaterialswound healingIn article number 2004886, Xiaowei Xu, Ding Zhou, Hongchen Sun, and co﹚orkers synthesize carbon dots with excellent biocompatibility via microwave゛ssisted heating of ascorbic acid and polyethyleneimine. The synthesized carbon dots can induce the ...
Zhang, LiangYuan, XiaoliangLü, ZhongOncology Research Featuring Preclinical and Clinical Cancer TherapeuticsWu, H.; Wang, X.; Mo, N.; Zhang, L.; Yuan, X.; Lu, Z. B7-homolog 4 promotes epithelial-mesenchymal transition and invasion of bladder cancer cells via activation of nuclear factor-...
Li, M.Hering-Smith, K.Simon, E. E.Batuman, V.Journal of Investigative MedicineM Hering--Smith, E, E Simon. Myeloma light chains induce ep- ithelial mesenchymal transition in human renal proximal tubule ep- ithelial cells[J]. Nephrol Dial Transplant,2008,23(3) :860-870....
FBXW FBXW 7 suppresses epithelial‐mesenchymal transition and chemo‐resistance of non‐small‐cell lung cancer cells by targeting snai1 for ubiquitin‐dep... FBXW FBXW 7 suppresses epithelial‐mesenchymal transition and chemo‐resistance of non‐small‐cell lung cancer cells by targeting snai1 for ub...
microRNA‐206 overexpression inhibits epithelial‐mesenchymal transition and glomerulosclerosis in rats with chronic kidney disease by inhibiting JAK/STAT signaling pathway Journal of Cellular Biochemistry (2019) -2Comments doi: 10.1002/jcb.28722 issn: 0730-2312 issn: 1097-4644 pubmed: 31148248 ...
In our study, miR‐363‐3p overexpression inhibited cell migration and invasion via epithelial–mesenchymal transition inhibition, while miR‐363‐3p knockdown exhibited the opposite effects. Further studies demonstrated that miR‐363‐3p bound to 3′‐untranslated regions of NEDD9 and SOX4, and ...