This month's Trends in Microbiology includes a free poster entitled 'Mechanisms of Antibiotic Action and Resistance' by Christopher T. Walsh, John W. Trauger, Patrice Courvalin and Julian E. Davies, which outlines the targets of a variety of antibiotics and three basic mechanisms of antibiotic ...
Antibiotic resistance is a global health emergency, with resistance detected to all antibiotics currently in clinical use and only a few novel drugs in the pipeline. Understanding the molecular mechanisms that bacteria use to resist the action of antimicrobials is critical to recognize global patterns ...
mechanism of action (redirected fromMechanisms of action) Medical mech´an`ism of ac´tion n.1.(Medicine, Biochemistry)The mechanism{2} by which a pharmacologically active substance produces an effect on a living organism or in a biochemical system; as, themechanism of actionof actinomycin in...
Molecular mechanisms of antibiotic action. 来自 NCBI 喜欢 0 阅读量: 41 作者: W Carter,KS Mccarty 展开 摘要: Summarizes the probable loci of action of a number of antibiotics and postulates how these drugs may be metabolized differently by the bacterial and host cell. Antibiotics that ...
Binding behavior of receptor binding domain of the SARS-CoV-2 virus and ivermectin Kasidy R. Gossen Meiyi Zhang Maria D. King Scientific Reports(2024) From antibiotic to antiviral: computational screening reveals a multi-targeting antibiotic from Streptomyces spp. against Nipah virus fusion proteins ...
As the field of nanomedicine emerges, there is a lag in research surrounding the topic of nanoparticle (NP) toxicity, particularly concerned with mechanisms of action. The continuous emergence of bacterial resistance has challenged the research community to develop novel antibiotic agents. Metal NPs ar...
To investigate the possible mechanisms of action of alkaloids against fungi, spore germination and mycelial morphology of M. oryzae, the mycelia treated with sanguinarine were studied by optical microscope and scanning electron microscope observations. Then, the modes of action were investigated by ...
Mechanisms of actionPathogenic enterobacteriaWeaning pigletsIn the last few decades, long-term and high-dose usage of antibiotics in livestock diets has led to the emergence of antibiotic resistant bacteria, antibiotic residues in animal products and environmental pollution, adversely affecting animal ...
116 erythromycin is a 13-carbon antibiotic belonging to the macrolide family. the gastrointestinal adverse effects induced by this antibiotic include abdominal cramping, nausea, vomiting, and diarrhea. erythromycin is a motilin receptor agonist that binds to gastrointestinal smooth-muscle membrane receptors...
We also describe how biofilms can evolve antibiotic resistance and transfer resistance genes within biofilms. Multispecies biofilms and the impacts of various interactions, including cooperation and competition, between species on tolerance to antimicrobials in polymicrobial biofilm communities are also ...