Buzyn A,Petit F,Ostankovitch M,Figueiredo S,Varet B,Guillet JG,Ameisen JC,Estaquier J.Membrane-bound Fas (Apo-1/CD95) ligand on leukemic cells:A mechanism of tumor immune escape in leukemia patients. Blood . 1999Buzyn A,Petit F,Ostankovitch M,et al.Membrane-bound Fas(Apo-1/CD95...
Abstract A58: JAK1 deficiency as a novel mechanism of tumor immune escape in uterine cancer doi:10.1158/2326-6074.TUMIMM14-A58Recognition of MHC class I antigens on the surface of tumor cells is an essential process in the effector phase of CD8+ cytotoxic T lymphocyte (CTL)-mediated anti-...
ACTIVATION INDUCED CELL DEATH (AICD) IN T LYMPHOCYTES FROM PATIENTS WITH RENAL CELL CARCINOMA (RCC): A POTENTIAL MECHANISM OF TUMOR IMMUNE ESCAPE 来自 ResearchGate 喜欢 0 阅读量: 11 作者:A. Michele Ward,Robert G. Uzzo,Tracy E. Bloom,Patricia A. Rayman,James H. Finke ...
Abstract 1560: Loss-of-function JAK1 mutations reveal a new role of protein tyrosine kinase mutations in human cancer Our findings suggest that JAK1 is a PTK tumor suppressor and reveal a novel mechanism of tumor immune evasion via LOF mutations in a PTK.doi:10.1158/1538-7445.AM2014-1560...
example, it may be possible that compounds inside the bacterial extracts had ability to directly kill cancer cells [5], or to preferentially inhibit tumor angiogenesis [6]. Accordingly, in our discussion of whether the immune response actually inhibits cancer or not, we will turn to animal ...
The activity of neurons in the vicinity of tumors is linked to a spectrum of cellular mechanisms, including the facilitation of tumor cell proliferation, synapse formation, angiogenesis, and macrophage polarization. This review consolidates the current u
The immune system plays a pivotal role in targeting cancer cells for destruction. However, tumor cells are smart and have developed ways to avoid immune detection. A collaborative team of researchers at Moffitt Cancer Center recently discovered a novel m
Immune Modulatory microRNAs Involved in Tumor Attack and Tumor Immune Escape Abstract Current therapies against cancer utilize the patient's immune system for tumor eradication. However, tumor cells can evade immune surveillance of CD8+ T and/or natural killer (NK) cells by various strategies. These...
The concept for cellular immunotherapy of solid tumors relies heavily on the capacity of class I MHC-restricted cytotoxic T lymphocytes (CTLs) to eliminate tumor cells. However, tumors often have managed to escape from the cytolytic machinery of these effector cells. Therefore, it is very importan...
Noun1.escape mechanism- a form of behavior that evades unpleasant realities dodging,escape,evasion- nonperformance of something distasteful (as by deceit or trickery) that you are supposed to do; "his evasion of his clear duty was reprehensible"; "that escape from the consequences is possible bu...