This chapter elaborates the mechanism of the action of antibiotics. Antibacterial antibiotics can be broadly classified according to their specific site and the mode of action as inhibitors of respiration and oxidative phosphorylation, cell-wall mucopeptide synthesis, cell membrane function, nucleic acid...
The detailed mechanisms of action of bactericidal antibiotics remain unclear. Here, Wong et al. show that these antibiotics induce cytoplasmic condensation through membrane damage and outflow of cytoplasmic contents, as well as accumulation of reactive metabolic by-products and lipid peroxidation, as par...
Besides antibacterial activities, AMPs have been found to possess a variety of biological functions, such as immune regulation, angiogenesis, wound healing and antitumor activity [6,7,8,9]. The treatment of pathogenic bacteria has been long-time mainly relied on antibiotics. However, the emergence...
来源期刊 Phytotoxins in Plant Diseases; Proceedings of the NATO Advanced Study Institute 1972 研究点推荐 phytotoxins antibiotics 引用走势 1976 被引量:1 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在这里我们保持学习的态度,不忘初心...
The most recent and important developments have been in the field of azole derivatives, the polyene antibiotics and their delivery by liposomes, and the drugs aimed against the fungal cell wall. With regard to other antifungal drugs and their mechanism of action, no significant progress has been ...
Vancomycin, like other antibiotics, also decreases the efficacy of estrogen-based contraception. Tabatha, a young woman in her twenties, comes into your office with colitis. She is sexually active and takes the pill to prevent pregnancy. Although vancomycin would be a good choice for her colitis...
fluoroquinolone, resulting in bacteriostasis and ultimate cell death through oxidative stress20. However, since many different classes of antibiotics converge on similar observations, the combination of each cellular parameter must be examined individually to determine the likely mechanism of action in any...
Mechanism of action of aminoglycoside antibiotics. Binding studies of tobramycin and its 6'-N-acetyl derivative to the bacterial ribosome and its subunits. Eur J of Biochem / FEBS. 1979; 102 (1):73–81. doi: 10.1111/j.1432-1033.1979.tb06264.x. [ Cross Ref ]...
Many antibiotics appear to have as their mechanism of action the capacity to inhibit bacterial cell wall synthesis. This does NOT appear to be a mechanism of A. Aminoglycosides B. Penicillins C. Bacitracin D. Cephalosporins E. Vancomycin
Some of the factors contributing to increased infections in immunocompromised patients include the use of intravenous catheters, invasive procedures, and total parenteral nutrition and the increasing use of broad-spectrum antibiotics, cytotoxic chemotherapies, and transplantation [7]. The virulence factors ...