MCF10A细胞在RLO处理后，p53、Caspase-3、DMP1和p21的表达水平显著提高，而HER2的表达水平降低[6]。这些变化表明MCF10A细胞在受到特定化学物质刺激时，其信号通路和功能会发生调整，从而影响细胞的增殖和凋亡。在与乳腺癌细胞共培养后，MCF10A细胞表现出多种癌症相关途径的显著失调，包括代谢途径、细胞粘附、生长因子信...
3.信号通路和功能: MCF10A细胞在RLO处理后,p53、Caspase-3、DMP1和p21的表达水平显著提高,而HER2的表达水平降低[6]。这些变化表明MCF10A细胞在受到特定化学物质刺激时,其信号通路和功能会发生调整,从而影响细胞的增殖和凋亡。 在与乳腺癌细胞共培养后,MCF10A细胞表现出多种癌症相关途径的显著失调,包括代谢途径、细...
GT1182CMCF7人乳腺癌细胞(非三阴)Her2阴性,ER阳性。MCF71500MEM+10%FBS+0.01mg/mL胰岛素+1%P/S贴壁 GT1183CMDAKB2人乳腺癌细胞(三阴性)MDAKB21500L15+10%FBS+1%P/S贴壁 GT1184CMDAMB157人乳腺癌细胞(三阴性)MDAMB1571500L15+10%FBS+1%P/S贴壁 ...
Differential expression of centrosome regulators in Her2+ breast cancer cells versus non- tumorigenic MCF10A cells. Cell Div. 2014;9:3.Lee MY, Marina M, King JL, et al (2014). Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells. ...
SK-BR-3细胞系;细胞传代方法:消化3-5分钟,1:2,3天内可长满;细胞形态特性:上皮样;细胞生长特性:贴壁生长;细胞背景资料:这株细胞源自胸水。没有病毒颗粒。亚显微结构特征包括微丝和桥粒,肝糖原颗粒,大溶酶体,成束的细胞质纤丝。SK-BR-3细胞株过表达HER2/c-erb-2基因产物。
(Bag-1S, Bag-1M and Bag-1L) in MCF-10A cells leads to the formation of lumenless acini, through attenuation of anoikis in BM-detached cells, without the grape-like abnormalities in morphology seen with HER2 overexpression.38 However, there is currently no evidence on the ability of ...
R. et al. Modeling ductal carcinoma in situ: A HER2–Notch3 collaboration enables luminal filling. Oncogene 31(7), 907–917. https://doi.org/10.1038/onc.2011.279 (2012). Article PubMed CAS Google Scholar Geissler, K. & Zach, O. Pathways involved in Drosophila and human cancer ...
HOXB8 and HOXB9 expression profiles in cell lines extensively used in the literature addressing the putative role of HOXB genes in breast cancer (MCF7, BT474, SKBR3, MDA231 and MDA468) and representative of the clinical breast cancer molecular subtypes (Luminal A, Luminal B, HER2+ and Tripl...
MCF10A细胞在RLO处理后,p53、Caspase-3、DMP1和p21的表达水平显著提高,而HER2的表达水平降低[6]。这些变化表明MCF10A细胞在受到特定化学物质刺激时,其信号通路和功能会发生调整,从而影响细胞的增殖和凋亡。 在与乳腺癌细胞共培养后,MCF10A细胞表现出多种癌症相关途径的显著失调,包括代谢途径、细胞粘附、生长因子信号...
Previous studies indicated that RECK expression is a com- mon target of repression by various oncogenic signals (such as HER2, Ras, Src, PI3K, and hypoxia) via multiple mechanisms (such as tran- scriptional repression, DNA methylation, and microRNAs)6,19,30–34. The results of our present...