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The long non-coding RNA X-inactive specific transcript (XIST) mediates the transcriptional silencing of genes on the X chromosome. Here we show that, in human cells, XIST is highly methylated with at least 78 N6-methyladenosine (m6A) residues—a reversib
M6A RNA methylation promotes XIST-mediated transcriptional repression. Nature 2016;537:369-73.Patil DP, Chen CK, Pickering BF, Chow A, Jackson C, Guttman M, Jaffrey SR. m6A RNA methylation promotes XIST-mediated transcriptional repression. Nature. 2016;537:369-73....
5. Patil, D.P., Chen, C.-K., Pickering, B.F., Chow, A., Jackson, C., Guttman, M., and Jaffrey, S.R. (2016). m 6 A RNA methylation promotes XIST-mediated transcriptional repression.Nature537, 369. 6...
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m6A RNA methylation promotes XIST-mediated transcriptional repression. Nature, 2016, 537: 369–373 20 Guo J, Tang H W, Li J, et al. Xio is a component of the Drosophila sex determination pathway and RNA N6-methyladenosine methyltransferase complex. Proc Natl Acad Sci USA, 2018, 115: 3674...