A panel of 511 immune- response genes was analyzed for each biopsy. Data were log2 transformed and quartile normalization was used to normalize data across samples. A linear model was used to compare the four groups (normal/CR/PR/NR) at baseline and a paired t test was used to compare ...
Jacob N, Yang H, Pricop L, Liu Y, Gao X, Zheng SG, et al. Accelerated pathological and clinical nephritis in systemic lupus erythematosus-prone New Zealand Mixed 2328 mice doubly deficient in TNF receptor 1 and TNF receptor 2 via a Th17-associated pathway. J Immunol. 2009;182(4):2532–...
The first panel shows the number of patients in the evaluation given the threshold; the second and third panels show the corresponding Pearson r and two-tailed p value (shown as -log10(p)). Extended Data Fig. 6 Evaluating the predictive capacity and information overlap among the TGSig, SLE...
2 Composite graphs depicting response to rituximab therapy on clinical parameters. Panel a SLEDAI [13] scores before and after rituximab ther- apy. Panel b proteinuria (Upr/cr) before and after rituximab. Panel c auto-antibody titers be- fore and after rituximab. Panel d serum complements as ...