These same signatures evaluated at clinical quiescence are correlated with disease activity in patients with systemic lupus erythematosus with plasmablast-associated flares. CITE-seq profiling of 82 surface proteins and transcriptomes of 53,201 single cells from healthy high and low influenza vaccination ...
An interferon signature is seen in the skin and frequently in the blood with patients with cutaneous lupus, and this correlates with the activity of lupus in the skin. There is evidence that medications are a frequent trigger of subacute cutaneous lupus, with about one-third of patients having...
Ricker DM, Hebert LA, Rohde R, Sedmak DD, Lewis EJ, Clough JD. Serum C3 levels are diagnostically more sensitive and specific for systemic lupus erythematosus activity than are serum C4 levels. The Lupus Nephritis Collaborative Study Group. Am J Kidney Dis. 1991;18(6):678–85. PubMedCASG...
Panel c auto-antibody titers be- fore and after rituximab. Panel d serum complements as C3 and C4 complements. Asterisks in- dicate significant differences from the post-rituximab values; P < 0.01 417 developed symptoms of cerebral vasculitis, with seizures and a cerebral infarct, demonstrated by...