相比之下,植物长链非编码RNA(long non-coding RNA, lncRNAs)的研究就相对落后,但是近几年的发展也是不容小… 伯远生物 大家都知道,RNA世界有三宝:miRNA、lncRNA和circRNA,无论是其中哪一个,均有众多的科研者对其进行孜孜不断的探索与追求 大家都知道,RNA世界有三宝:miRNA、lncRNA和circRNA。无论是其中哪一个,...
名词解释长非编码 RNA(long non-coding RNA,IncRNA) 答案 长非编码RNA:是一类长度为200~100000个核苷酸的RNA分子。lncRNA由RNA聚合酶Ⅱ转录生成,经剪切加工后,形成具有类似于mRNA的结构。lncRNA有poly(A)尾和启动子,但序列中不存在可读框,不编码任何蛋白质。lncRNA具有调控的多样性,可从染色质重塑、转录调控及转...
LncRNA(Long non-coding RNAs)是一类长度大于200nt但不编码蛋白质,广泛存在于动植物中,具有很强的细胞或组织特异性的RNA分子。IncRNA测序可一次性获取样本中几乎全部的IncRNA信息,对IncRNA的类别、功能进行全方位的深入分析,从而快速全面准确的获得与特定生物学过程相关的IncRNA信息。
Long Non-Coding RNA 生物学 | 书籍 |1.1-1.5 《Long Non-Coding RNA Biology》是一本由M.R.S. Rao著的专业书籍,该书于2017年由Springer出版社出版。原著中说明了可以用于交流学习,不涉及商业用途就可以,因此不存在侵权问题。 本书是关于长非编码RNA(lncRNA)的综合性教材,涵盖了lncRNA的多个方面,包括结构、...
LncRNA (Long non-coding RNA) is a class of non-coding RNA molecules with lengths exceeding 200 nucleotides and lacking protein-coding functions.
近日,哈佛大学、麻省总医院朱肇中团队采用RNA转录组学(RNA sequencing)研究方法,发现在患重症细支气管炎的婴儿中,其鼻咽部气道内的一些long non-coding RNA(lncRNA)的变化与呼吸道病毒感染、儿童哮喘的风险因素和lncRNA调控的表观遗传学...
Long non-coding RNAs (lncRNAs) are thought to encompass nearly 30,000 different transcripts in humans, hence lncRNA transcripts account for the major part of the non-coding transcriptome. lncRNA discovery is still at an early stage and only a small proportion of lncRNAs have so far been inves...
Messenger RNAs transcribed from olfactory-receptor genes may have non-coding functions that include recruitment of transcriptional enhancers and inhibition of potentially thousands of competing alleles to ensure stable transcription of a single allele. Ariel D. Pourmorady , Elizaveta V. Bashkirova & Stav...
Enormous studies have corroborated that long non-coding RNAs (lncRNAs) extensively participate in crucial physiological processes such as metabolism and immunity, and are closely related to the occurrence and development of tumors, cardiovascular diseases, nervous system disorders, nephropathy, and other di...
Stroke is one of the leading causes of mortality and disability worldwide. Uncovering the cellular and molecular pathophysiological processes in stroke have been a top priority. Long non-coding (lnc) RNAs play critical roles in different kinds of diseases. In recent years, a bulk of aberrantly ...