Long non-coding RNAs in cancerdoi:10.1016/j.ncrna.2019.02.003Kim, Mi-YoungNon Coding Rna Research
长链基因间lncRNA(Long intergenic lncRNAs,lincRNAs),以LINC为前缀,数字为后缀,例如LINC00485. 本质上以上命名原则是以GNECODE的注释目录为基准, 反义RNA,正义内含子,正义重叠和长链基因间非编码RNA(lincRNA).一些新的分类方法也应该考虑,特别对这些lnRNA,它们与编码基因是头 碰头(head to head),因此推断它们拥...
名词解释长非编码 RNA(long non-coding RNA,IncRNA) 答案 长非编码RNA:是一类长度为200~100000个核苷酸的RNA分子。lncRNA由RNA聚合酶Ⅱ转录生成,经剪切加工后,形成具有类似于mRNA的结构。lncRNA有poly(A)尾和启动子,但序列中不存在可读框,不编码任何蛋白质。lncRNA具有调控的多样性,可从染色质重塑、转录调控及转...
codingcancerrnalncrna长非emerging REVIEWARTICLEEmergingrolesoflongnon-codingRNAincancerAnnaSanchezCalle1|YumiKawamura1,2|YusukeYamamoto1|FumitakaTakeshita3|TakahiroOchiya1,41DivisionofMolecularandCellularMedicine,NationalCancerCenterResearchInstitute,Tokyo,Japan2Ph.D.PrograminHumanBiology,SchoolofIntegrativeandGlobalMa...
Esophageal cancer (EC) is the sixth leading cause of cancer-related death worldwide. The lack of early diagnostic biomarkers and effective prognostic indicators for metastasis and recurrence has resulted in the poor prognosis of EC. In addition, the unde
longnon coding rna名词解释 Long noncoding RNA(LncRNA)是一类长度大于200个核苷酸的长链非编码RNA。它属于非编码基因组的重要组成部分,一些LncRNA的长度甚至超过90kb,被称为macroRNA。研究表明,LncRNA在剂量补偿效应、表观遗传调控、细胞周期调控和细胞分化调控等众多生命活动中发挥重要作用,成为遗传学研究的热点。
Long Noncoding RNA Long noncodingRNA(lncRNA) is an emerging area of focus in prostatecancer biology, and recenttranscriptomicprofiling studies have identified sets of lncRNAs associated with prostate cancer[21,22]. Some lncRNAs, such asPCAT-1andPCAT29, have novel oncogenic or tumor-suppressor rol...
Exosomal long noncoding RNA LNMAT2 promotes lymphatic metastasis in bladder 1 cancer 本文选自看不懂的杂志,一起看看得了,应该没有什么花样。 摘要:有临床淋巴结转移的膀胱癌患者预后极差。VEGF-C在BCa淋巴结转移中起重要作用。然而,约20%有淋巴结转移的BCa中VEGF-C表达较低,提示BCa的LN转移与VEGF-C无关...
《Long Non-Coding RNA Biology》是一本由M.R.S. Rao著的专业书籍,该书于2017年由Springer出版社出版。原著中说明了可以用于交流学习,不涉及商业用途就可以,因此不存在侵权问题。 本书是关于长非编码RNA(lncRNA)的综合性教材,涵盖了lncRNA的多个方面,包括结构、功能、调节机制、疾病相关性等等。该书共分为10章...
The invention described in the application relates to a long non-coding RNA expressed in cancer. The invention thus provides methods and compositions for evaluating levels of the long non-coding RNA to assess the aggressiveness of a cancer and for modulating levels of the long non-coding RNA....