结果lncRNA MM2P高表达于M2型巨噬细胞(P<0.001),并且lncRNA MM2P在胃癌细胞株及其外泌体中的表达水平均显著高于其在胃黏膜上皮细胞及其外泌体中的表达(P<0.001).与Vector组比较,转染lncRNA MM2P后,M2型巨噬细胞标志蛋白CD206,CD163,IL-10表达显著上调(P<0.001).与GES-1 exo组比较,MGC-803 exo组和SGC...
研究发现:lncRNA NIFK-AS1、CCAT1、Linc-p21和COX2抑制巨噬细胞M2极化,而lncRNA MIR155HG和GAS5可促进巨噬细胞M1极化,具有促炎效应;lncRNA H19、NEAT1和NRON抑制巨噬细胞M1极化,而lncRNA SNHG20、MM2P、KCNQ1OT1、RP11-361F15.2、G...
结果lncRNA MM2P高表达于M2型巨噬细胞(P<0.001),并且lncRNA MM2P在胃癌细胞株及其外泌体中的表达水平均显著高于其在胃黏膜上皮细胞及其外泌体中的表达(P<0.001).与Vector组比较,转染lncRNA MM2P后,M2型巨噬细胞标志蛋白CD206,CD163,IL-10表达显著上调(P<0.001).与GES-1 exo组比较,MGC-803 exo组和SGC...
There are comments on PubPeer for publication: LncRNA-MM2P Identified as a Modulator of Macrophage M2 Polarization (2019)
LncRNA MM2P-induced, exosome-mediated transfer of Sox9 from monocyte-derived cells modulates primary chondrocytes Cell Death Dis., 11 (9) (2020), Article 763 View in ScopusGoogle Scholar [23] H. Xue, P. Yu, W.Z. Wang, et al. The reduced lncRNA NKILA inhibited proliferation and promoted...
LncRNA MEG3调节MDM2通过P53信号通路影响缺血性脑卒中
LBX2 antisense RNA 1 (LBX2-AS1), transcribed from the intron of chromosome 2p13.1, is a newly discovered lncRNA which was initially reported to act as a tumor promoter and predict poor prognosis of esophageal squamous cell carcinoma patients [16]. Moreover, it was reported that upregulation...
We then assessed the function of theLncRIM-NF2 axis in cellular iron metabolism. Interestingly, we found that overexpression of either the full-lengthLncRIMor the S1 truncation loop sufficiently restored the cellular iron level inLncRIM-silenced cells (Fig.2p) and reversed the phosphorylation of YA...
RNA samples (30 μg) were resolved in formaldehyde agarose in gel running buffer [0.1 M MOPS (pH 7.0), 40 mM sodium acetate, 5 mM EDTA (pH 8.0)] and 37% formaldehyde at 4 V/cm. The RNA was transferred on to GeneScreen plus (NEN) nylon membranes. Probe was prepared ...
Meanwhile, LDLR expression (Figures 2P and 2R) and TG content (Figure 2S) in fish hepatocytes were increased by TNFα. Overall, these results suggested that PA-induced TNFα promoted SREBP2 into the nucleus to regulate LDLR transcription. Identification and characterization of LDLR-AS as a ...