Wesley, B.T., Ross, A.D.B., Muraro, D.et al.Single-cell atlas of human liver development reveals pathways directing hepatic cell fates.Nat Cell Biol24, 1487–1498 (2022). https://doi.org/10.1038/s41556-022-00989-7 Download citation ...
A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapyMETASTASISCOLON cancerSTROMAL cellsCANCER chemotherapyTUMORSMetastasis is the primary cause of cancer-related mortality in colorectal cancer (CRC) patients. ...
We here generated a single-cell atlas of intrahepatic T cells in PSC, a type of immune cells that has previously been involved in the pathogenesis of PSC. This atlas provides a valuable data source to the field. Using that atlas, we identified a population of liver-resident naive-like CD4...
Owing to its high accuracy and specificity, scRNA-seq has become an ideal research tool for single cell study [29]. Unbiased high-throughput research can be performed with a minimum starting sample volume. ScRNA-seq can be used alongside multiomics to simultaneously analyse the genome, transcripto...
berghei single-cell transcriptomes P. vivax cells were compared with a subset of the mouse Malaria Cell Atlas dataset (liver and blood asexual and sexual stages; https://zenodo.org/record/2843883#.Ygz7wC-l1bU) using the scmapCell() function in scmap (v 1.14.0) (Kiselev et al., 2018)...
et al. A single cell atlas of the human liver tumor microenvironment. Mol. Syst. Biol. 16, e9682 (2020). Article CAS PubMed PubMed Central Google Scholar Andrews, T. S. et al. Single cell, single nucleus, and spatial RNA sequencing of the human liver identifies hepatic stellate cell...
et al. A multi-omics approach to liver diseases: integration of single nuclei transcriptomics with proteomics and HiCap bulk data in human liver. OMICS 24, 180–194 (2020). Article CAS PubMed PubMed Central Google Scholar Massalha, H. et al. A single cell atlas of the human liver ...
N.A. designed, optimized and performed cell sorting, scRNA-seq, organoid culture and immunofluorescence, provided validation using the Human Protein Atlas, and performed computational analysis and interpretation of the data. A.S. managed the supply of patient material, isolated single cells from ...
Phenotypic characterization of liver tissue heterogeneity through a next-generation 3D single-cell atlas Dilan Martínez-Torres , Valentina Maldonado & Fabián Segovia-Miranda Article 29 January 2024 | Open Access Comprehensive bile acid pool analysis during ex-vivo liver perfusion in a porcine model...
Single-cell atlas of zebrafish livers To investigate the diversity of zebrafish liver cell types, adult zebrafish livers were prepared for the construction of single-cell libraries using the MGI2000 platform (Fig. 1A). Six single-cell libraries were sequenced at a median of 78,178 reads per cel...