Publisher’s noteSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. About this article Cite this article Wesley, B.T., Ross, A.D.B., Muraro, D.et al.Single-cell atlas of human liver development reveals pathways directing hepatic...
the cellular composition of the liver remains poorly understood. Here we performed single-cell RNA sequencing of about 10,000 cells from normal liver tissue from nine human donors to construct a human liver cell atlas. Our analysis identified...
the cellular composition of the liver remains poorly understood. Here we performed single-cell RNA sequencing of about 10,000 cells from normal liver tissue from nine human donors to construct a human liver cell atlas. Our analysis identified...
et al. A single cell atlas of the human liver tumor microenvironment. Mol. Syst. Biol. 16, e9682 (2020). Article CAS PubMed PubMed Central Google Scholar Andrews, T. S. et al. Single cell, single nucleus, and spatial RNA sequencing of the human liver identifies hepatic stellate cell...
Phenotypic characterization of liver tissue heterogeneity through a next-generation 3D single-cell atlas Dilan Martínez-Torres , Valentina Maldonado & Fabián Segovia-Miranda Article 29 January 2024 | Open Access Comprehensive bile acid pool analysis during ex-vivo liver perfusion in a porcine model...
Single-nucleus RNA-seq libraries were prepared using the following: Chromium Single Cell 3′ Library and Gel Bead Kit v.3.1, Chromium Chip G Kit and Chromium Single Cell 3′ Reagent Kits v.3.1 User Guide (manual part CG000316 Rev A; 10x Genomics). One sample was run per lane of the ...
This study first explored TME heterogeneity between primary lesions (PL) and LM to construct a comprehensive single-cell atlas of CRNELM patients, which was validated through multidimensional analyses, including spatial transcriptomics (ST), bulk RNA sequencing, and multiplex immunohistochemistry/immunofluore...
cell atlas in both healthy and diseased states is needed for new therapeutic target development and disease intervention improvement. With the development of high-throughput single-cell technology, we can now decipher heterogeneity, differentiation, and intercellular communication at the single-cell level ...
Single-cell atlas of zebrafish livers To investigate the diversity of zebrafish liver cell types, adult zebrafish livers were prepared for the construction of single-cell libraries using the MGI2000 platform (Fig. 1A). Six single-cell libraries were sequenced at a median of 78,178 reads per cel...
The human liver is an essential multifunctional organ. The incidence of liver diseases is rising and there are limited treatment options. However, the cellular composition of the liver remains poorly understood. Here we performed single-cell RNA sequenci