LACE - R package for Longitudinal Analysis of Cancer Evolution using mutations called from scRNA-seq data. Input - binary matrix with 1 indicating somatic variants, called using GATK. Boolean matrix factorization solved via exhaustive search or via MCMC. Output - the maximum likelihood clonal tree ...
Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families. Am J Hum Genet 1998;63:1341–1351. 38. Struewing JP, Hartge P, Wacholder S, et al. The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N Engl J ...
PURPOSE: Women who carry germline mutations in the BRCA1 and BRCA2 genes are at greatly increased risk of breast cancer (BC). Numerous studies have shown t... Andrieu,N. 被引量: 140发表: 2006年 Treatment of gout with allopurinol. A study of 106 cases. Top of pageMaterial and methods ...
Heterogeneity of resistance mutations detectable by next-generation sequencing in TKI-treated lung adenocarcinoma.异质性的阻力突变被下一代测序在TKI-treated肺腺癌 热度: An investigation of gene-gene interactions in dose-response studies with Bayesian nonparametrics ...
mutations of genes BRCA1 and BRCA2 (linked to an increased risk of breast and ovarian cancers) can inhibit the body's ability to safeguard and repair DNA. Copies of these mutated genes can be passed on genetically to future generations, leading to a genetically-inherited increased risk of ...
mutations of genes BRCA1 and BRCA2 (linked to an increased risk of breast and ovarian cancers) can inhibit the body's ability to safeguard and repair DNA. Copies of these mutated genes can be passed on genetically to future generations, leading to a genetically-inherited increased risk of ...
Asilomar Attendee List 2003 Although germline mutations in BRCA1 play a central role in familial breast and ovarian cancers, to date, no somatic mutations in BRCA1 have been reported ... AS Grover,S Mittal,P Singla,... - 《Clinical Chemistry》 被引量: 0发表: 2004年 加载更多来源...
Hereditary breast and/or ovarian cancer 1.01.03.0 604370612555114480 BRCA1BRCA2PALB2 AD All P and LP Hereditary paraganglioma–pheochromocytoma syndrome 1.01.01.01.03.03.0 168000601650605373115310171300171300 SDHDSDHAF2SDHCSDHBMAXTMEM127 AD All P and LP Juvenile polyposis syndrome 2.02.0 174900175050 BMPR1A...
Definition of Anatomy Anatomy:The study of human or animal form, by observation or examination of the living being, examination ordissectionof dead specimens, microscopic examination, and/or textbooks.
The molecular weight is 384.24. The molecular formula is C19H25BN4O4. The solubility of bortezomib, as the monomeric boronic acid, in water is 3.3 to 3.8 mg/mL in a pH range of 2 to 6.5. VELCADE is available for intravenous injection or subcutaneous use. Each single-use vial contains ...