SCIEX LC-MS/MS solutions empower researchers to delve into the lipidome to meticulously characterize subtle distinctions between lipid species and screen similar compounds with enhanced clarity and confidence. Our mass spectrometry portfolio provides powerful tools that deliver precise and comprehensive insigh...
脂质的分析鉴定:生物质谱技术是目前脂质组学研究的核心工具,特别是液相色谱——质谱联用技术(LC-MS)和“鸟枪法”脂质组学技术(shotgun lipidomics),能够高效、准确地鉴定脂质分子。 生物信息学分析:利用生物信息学软件对质谱数据进行处理和分析,构建脂质代谢网络,揭示脂质代谢与生物体生理功能之间...
And LC-MS/MS based lipidomic analysiswas used to explore the characteristic placental lipids in mild and severe ICP. Results: Fourty-four lipids were differentially expressed both in mild and severe ICP placenta. The pathway analysis revealed these lipids are mainly enriched in...
LC, MS and MS/MS — necessitate the use of multiple software programs to automate data analysis. There is no informatics suite that supports automated data analysis of all the above mentioned methods.SimLipid softwarehas been developed to allows users to not only analyze data from these methods,...
Liquid chromatography–tandem mass spectrometry (LC–MS/MS) Lipids from plasma samples were extracted using a 1-butanol:methanol (1:1, v/v, Merck Millipore) extraction solvent containing a set of internal standards based on a method previously described [24]. Briefly, 100 μl of extraction sol...
In this study, a liquid chromatography (LC)-mass spectrometry (MS)-based lipidomics approach was used to discriminate chicken meat and abdominal fat from different sources. OxPC (16:0-20:4+1O(1Cyc)) and PC (18:2/20:5) were determined as the discriminatory markers for the meat of ...
Henein, MichaelRuiVorkas, Panagiotis A.Elsevier Ireland LtdInternational Journal of CardiologyDjekic, D., Pinto, R., Vorkas, P. A. and Henein, M. Y. (2016). Replication of LC-MS untargeted lipidomics results in patients with calcific coronary disease: An interlaboratory reproducibility study....
Quantification of Endogenous Endocannabinoids by LC-MS/MS Mesut Bilgin, Andrej Shevchenko Pages 99-107 Lipid Profiling by Supercritical Fluid Chromatography/Mass Spectrometry Takayuki Yamada, Takeshi Bamba Pages 109-131 Mass Spectrometric Analysis of Lipid Hydroperoxides ...
The study of lipid biology is undergoing a remarkable, technology-driven transformation that most notably involves mass spectrometry (MS) and its ancillary techniques, such as liquid chromatography (LC) and ionization sources. Greater investment inflows and a surge of activity, especially in the field...
质谱(MS)是脂质组学研究的主导平台,核磁共振(NMR)在代谢组学研究中得到了广泛的应用。气相色谱-质谱(GC -MS)是过去脂质谱研究的主要工具。然而,这项技术已经取代了大气压电离的解吸电离技术的接口(API)和matrix-assisted激光解吸电离(MALDI) / API,女士通常电喷雾电离(ESI),通常与液相色谱系统(LC)女士之前分离...