Second, improvement of computer power and simulation techniques allowed an extended exploration of the interaction of realistic macromolecules. Third, simultaneous development of a variety of techniques based on atomic force microscopy, hydrodynamic flow, biomembrane probes, optical tweezers, magnetic fields ...
JohnAndrewsand Carol ine Russel lambridgeAntibodyTechnology,Mi lstein Bui lding,Granta Park,Cambridge,CB21 6GH,UKval uation of a new HTRF®acceptor ..
Second, improvement of computer power and simulation techniques allowed extended exploration of the interaction of realistic macromolecules. Third, simultaneous development of a variety of techniques based on atomic force microscopy, hydrodynamic flow, biomembrane probes, optical tweezers, magnetic fields or ...
5) receptor-receptor interaction 受体-受体之间相互作用6) weak interaction 配体间相互作用补充资料:放射配体受体分析 分子式:CAS号:性质:又称放射受体分析(radio receptor assay;RRA)。以受体蛋白作为特异性联结剂,测定激素(受体激动剂)的竞争性放射分析法的一种。激素受体是细胞内的一种蛋白质,它能与激素特异...
The interaction of CD40 ligand (CD40L) expressed by activated T cells with CD40 on macrophages has been shown to be a potent stimulus for the production of... PS Yamauchi,JR Bleharski,K Uyemura,... - 《Journal of Immunology》 被引量: 256发表: 2000年 Direct identification of ligand-recept...
Ligand-receptor interactions at the parathyroid hormone receptors: subtype binding selectivity is mediated via an interaction between residue 23 on the lig... Donnelly, Ligand-receptor interactions at the parathyroid hormone (PTH) receptors: subtype binding selectivity is mediated via an interaction ...
The rate of binding of a ligand to receptors on the cell surface can be diffusion limited. We analyze the kinetics of binding, diffusion-limited in a stationary liquid, in the presence of convective mass transport. We derive a formula that expresses the reaction kinetics in terms of the mass...
•thisligand-receptorinteractioninducesaconformational orshape-changeinthereceptor •producesaspecificresponse-calledthecellular response •canincludeavastarrayofcompounds –e.g.smallaminoacidderivatives,smallpeptides,proteins Cell-to-cellcommunicationbyextracellular signalingusuallyinvolvessixsteps •(1)...
Based on the amplitude of three-dimensional (3D) thermal position fluctuations of the attached bead, we were able to select for a bead-coverslip interaction that was mediated by a single streptavidin-biotin complex. Moreover, the developed experimental system was greatly accelerated by automation of...
The objective of this paper is to briefly outline in a non-technical way a mathematical model for some basic interaction mechanisms of importance in cell biology and immunology. We extend the existing analysis of receptor-ligand interactions and diffusion to include general geometric shapes for the ...