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摘要: Extensive description and analysis of receptor-ligand interactions, including how the number of potential binding sites on a receptor and the affinity of each binding site for its ligand may be determined.关键词: ELECTRICAL RESISTIVITY SUPERCONDUCTIVITY SUSCEPTIBILITY MEASUREMENTS ...
Design and use of fluorescent ligands to study ligand-receptor interactions in single living cells. The interaction of ligands with G protein-coupled receptors (GPCRs) has been traditionally studied using radiolabelled variants of receptor ligands. More r... SJ Briddon,B Kellam,SJ Hill - 《Method...
Ligand-receptor interaction analysis using CellChat in conjunction with differential expression analysis demonstrated differential expression and secretion of a ... S Denda,LF Reichardt,U Mü 被引量: 0发表: 2017年 加载更多来源期刊 Science 研究点推荐 CD44 Osteopontin 引用走势 2010 被引量:183 站内...
Theory predicts that the kinetics of simple interactions between a ligand and a receptor bound on the surface of a cell will be affected by the occupancy of receptors on the same cell. In a diffusion-limited reaction the effect will be on the rate of dissociation but not on the rate of ...
Ligand-receptor interactions at the parathyroid hormone receptors: subtype binding selectivity is mediated via an interaction between residue 23 on the lig... Donnelly, Ligand-receptor interactions at the parathyroid hormone (PTH) receptors: subtype binding selectivity is mediated via an interaction ...
Using typical numbers characterizing the ligand-receptor interactions, we show that stirring and perfusion can be important factors determining the reaction rates. With the confluent colony, the early reaction kinetics requires a different treatment, and we provide it for the case of low receptor ...
Recent mutagenesis experiments have identified some of the functional amino acids that are essential in the interaction of nicotinic agents with the binding site of the neural nicotinic acetylcholine receptor (nAChR). Although this receptor is one of the best studied and characterized the lack of deta...
The objective of this paper is to briefly outline in a non-technical way a mathematical model for some basic interaction mechanisms of importance in cell biology and immunology. We extend the existing analysis of receptor-ligand interactions and diffusion to include general geometric shapes for the ...