A system for the quantitative analysis of ligand-receptor interactions is presented, based on models of different levels of complexity. For two pools of receptors, binding of a radioactive ligand is described by b = [( B m1 路 A n1 )/( K d1 n1 + A n1 )] + [( B m2 路 A n2 ...
LIANA: a LIgand-receptor ANalysis frAmework. Contribute to saezlab/liana development by creating an account on GitHub.
Solid-State NMR Analysis of Ligand−Receptor Interactions Reveals an Induced Misfit in the Binding Site of Isorhodopsin 来自 ACS 喜欢 0 阅读量: 34 作者:Alain,F.,L.,Creemers,Petra,H.,M.,Bovee-Geurts,Willem,J.,DeGrip,Johan,Lugtenburg,Huub,J.,M.,de,Groot ...
Pharmacophore modeling and 3D quantitative structure-activity relationship analysis of febrifugine analogues as potent antimalarial agent Febrifugine and its derivatives are effective against Plasmodium falciparum. Using PHASE algorithm, a five-point pharmacophore model with two hydrogen bond... D Sen,TK ...
JohnAndrewsand Carol ine Russel lambridgeAntibodyTechnology,Mi lstein Bui lding,Granta Park,Cambridge,CB21 6GH,UKval uation of a new HTRF®acceptor ..
fixed31, e.g. in the coating of the influenza virus. In all these cases, our theoretical framework can be directly applied. When receptor (or ligand) mobility is high and can induce local changes of their grafting density, instead, a theoretical analysis of the binding mechanism should ...
(125/161 with unique probes on the arrays). We conclude that the remaining 184 proteins detected in the proteome data only, are most likely not produced by B cells but instead are either false positives of the proteome analysis or non-cell autonomous36contributions to the proteome. In ...
Single-molecule force spectroscopy: a method for quantitative analysis of ligand-receptor interactions. The quantitative analysis of molecular interactions is of high interest in medical research. Most methods for the investigation of ligand–receptor complex... A Fuhrmann,R Ros - 《Nanomedicine》 被引...
ANALYSIS OF LIGAND–RECEPTOR INTERACTIONS IN CELLS BY ATOMIC FORCE MICROSCOPY Atomic force microscopy (AFM) increasingly has been used to analyse "receptor" function, either by using purified proteins ("molecular recognition microsco... M Horton,G Charras,P Lehenkari - 《J Recept Signal Transduct...
ISCHIA is a framework for analysis of cell-types and Ligand-Receptor cooccurrences in spatial transcriptomics/proteomics data Installation You can install the development version of ISCHIA from GitHub with: # install.packages("devtools") devtools::install_github("ati-lz/ISCHIA") Example Here we pres...