Quehenberger P, Handler S, Mannhalter C, Kyrle PA, Speiser W. The factor V (Leiden) test: Evaluation of an assay based on dilute russell viper venom time for the detection of the factor V Leiden mutation. Thromb Res 1999;96:125-133....
GENETEST REVIEW Genetics in Medicine Factor V Leiden thrombophilia Jody Lynn Kujovich, MD TABLE OF CONTENTS Pathogenic mechanisms and molecular basis ...2 Prevalence...2 Diagnosis...
library("Seurat") FindClusters(pbmc_small) adjacency_matrix <- as.matrix(pbmc_small@snn) partition <- leiden(adjacency_matrix) pbmc_small@ident <- as.factor(partition) names(test@ident) <- rownames(test@meta.data) pbmc_small@meta.data$ident <- as.factor(partition) Seurat objects contain ...
Clinical specificity for the factor V Leiden test has not been firmly established, but can be no lower than 95% (this assumes that all 5% of the population with a mutation are clinical false positives). Similarly, the clinical specificity for the prothrom- bin test is likely to be no ...
Factor V Leiden-dependent APC resistance: Improved sensitivity and specificity of the APC resistance test by plasma dilution in factor V-depleted plasma The APC-r test had a sensitivity of 0.42 and a specificity of 0.91 for the detection of factor V Leiden. Furthermore, we found no significant...
Evaluation of a highly specific functional test for the detection of factor V Leiden. Values below 136 s were found in every sample from patients carrying the factor V Leiden mutation ( n =52), whereas no patient with protein C ( n ... P Quehenberger,S Handler,C Mannhalter,... - 《...
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We have detected by genotyping the factor V Leiden mutation on 5 082 clinical samples corresponding to patients at risk for venous thrombosis; 1 328 patients (26.1 %) were heterozygous and 47 (0.9 %) homozygous for the mutation. The genotypic test has shown superior performances compared to ...
abulk factor of component i and was taken to be 1. 大块因素组分i和被采取是1。[translate] a事实上,我更喜欢看篮球比赛 In fact, I like watching the basketball game[translate] ahow about going out for a walk around the lake? 出去为步行怎么样在湖附近?[translate] ...
Whether the factor V Leiden mutation increases the risk of recurrent venous thromboembolism (VTE) remains controversial, and homozygous carriers have not been extensively evaluated. In the present cohort study, we have assessed the incidence of recurrent VTE in a subset of non-treated patients previou...