The disclosed Factor V Ratio (FVR) screening blood assay (read as "factor five ratio") and kits for the conduct thereof, identify individuals that possess a specific genetic defect, known as the Factor V Leiden defect, or other genetic or acquired Factor V defect, that makes those ...
摘要:The disclosed Factor V Ratio (FVR) screening blood assay (read as "factor five ratio") and kits for the conduct thereof, identify individuals that possess a specific genetic defect, known as the Factor V Leiden defect, or other genetic or acquired Factor V defect, that makes those ...
Define factor II. factor II synonyms, factor II pronunciation, factor II translation, English dictionary definition of factor II. Noun 1. factor II - a protein in blood plasma that is the inactive precursor of thrombin prothrombin clotting factor, coagul
蛋白别名:Activated protein C cofactor; Coagulation factor V; coagulation factor V (proaccelerin, labile factor); coagulation factor V jinjiang A2 domain; Factor 5; factor V Leiden; Factor5; Proaccelerin, labile factor 基因别名:F5; FVL; PCCF; RPRGL1; THPH2 ...
The levels of vWF are influenced by inflammation, genetic influences (e.g., ABO blood groups), and a metalloprotease known as “A Disintegrin And Metalloprotease with ThromboSpondin motif (ADAMTS13).”29 When coupled with inflammation, high levels of vWF triple the relative risk of stroke ...
ABO blood group genotypes and the risk of venous thrombosis: effect of factor V Leiden Among the 471 patients, 92 (19.5%) carried factor (F)V Leiden compared with 14 (3.0%) of the 471 controls, yielding an OR for venous thrombosis of 7.9 (95%... VM Morelli,MCHD Visser,HL Vos,......
Blood 2002;99:3102–3110. 50. Grody WW, Griffin JH, Taylor AK, Korf BR, Heit JA, ACMG Factor V. Leiden Working Group. American College of Medical Genetics consensus statement on Factor V Leiden mutation testing. Genet Med 2001;3:139 –148. 51. Van Cott EM, Laposata M, Prins MH....
Patients with no evidence of an acute VTE, (neither by diagnostic imaging nor by Wells clinical criteria) that had a normal D-dimer test5, were referred as controls in the study. All participants were sampled before any anticoagulant treatment. Whole blood was collected at the same timepoint ...
A case-control comparison showed a significant risk of thrombosis in the presence of Factor V Leiden (OR = 10.1), which was approximately doubled when the AB alleles of the ABO blood group were present as well (OR = 22.3). These results confirm that the increased risk of deep vein ...
*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 (unpaired two-tailed t-test). Full size image Flow cytometry showed that in vitro treatment of blood-derived monocytes with FHR-1 resulted in a substantial increase in cell surface TF expression. This effect was inhibited by the ...