weretheheterozygousmice. Results Lck—Cre×Perp ’。 micewerebreedsuccessfullyandtheirgenotypewereidentifiedaccuratelybyPCR andwesternblot.TheexpressionlevelofPerpinspleenCD3 TlymphocytesofLck—Cre× Perp。 micewas significantlylower,comparedwiththatinLck—Cre ...
Med23flox/flox;Lck-Cre mice have normal thymic populations, but MED23 null T-cells poorly populate the peripheral lymphoid tissues.Lawryn, H. KasperTomofusa, FukuyamaPaul, K. Brindle
in the thymuses of Med23flox/flox;Lck-Cre mice were essentially normal, MED23 null T-cells failed to efficiently populate the peripheral lymphoid organs... LH Kasper,T Fukuyama,PK Brindle - 《Plos One》 被引量: 3发表: 2014年 T-cells null for the MED23 subunit of mediator express decrea...
【关键词】 Perp;Lck-Cre;Cre-LoxP系统【中图分类号】 R392.5 【文献标志码】 AReproductionandGenotyping oftheLck-Cre×Perpflox/flox ConditionalKnock-OutMice LENG Xiao1,ZHOU Yan2,TANG Hai-ming1,ZHANG Xiang1,LIU Jia1,YANG Pei1,WANG Yan-tang1* (1.Department ofImmunology,School of Basic Medical...
Pten flox/flox Lck-Cre mice developed thymic lymphomas, but before the onset of tumors, they showed normal thymic cellularity. To reveal a regulatory ... TJ Hagenbeek,M Naspetti,F Malergue,... - 《Journal of Experimental Medicine》
Taken together, the data presented in this study shed new light on gamma delta T cell development and stimulate a reanalysis of data generated using the pLckCre transgenic mice.Fiala, Gina J.Univ FreiburgSchaffer, Anna-MariaLeibniz Res Inst Environm MedMerches, KatjaMorath, AnnaSwann, JeremyHerr...