Find all the latest on metformin at Medical Xpress. Your go-to source for news, research, and medical breakthroughs.
MEDICAL researchCORONARY artery diseaseMETFORMINMYOCARDIAL injuryCARDIOVASCULAR diseasesBackground: Metformin is among the most frequently prescribed antidiabetic drugs worldwide and remains the first-line therapy for type 2 diabetes due to its well-established glucose-lowering efficacy and favorab...
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Variation in metformin pharmacokinetics Claire Greenhill Research Highlights03 Apr 2023Nature Reviews Endocrinology Volume: 19, P: 314 Pharmacokinetic modelling using linked organ chips Ellen F. Carney Research Highlights10 Feb 2020Nature Reviews Nephrology ...
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ResearchOpen Access28 Dec 2024 Scientific Reports Volume: 14, P: 31316 Metformin in gestational diabetes: physiological actions and clinical applications This Review outlines the complex actions of metformin in metabolic regulation, providing a plausible basis for its benefits in the management of ges...
Therefore, this article reviews the methods and mechanisms for breaking through the BBB, as well as the current research progress on this mechanism. Keywords: cerebrovascular disease; blood–brain barrier; passive diffusion; receptor-mediated transport; adsorption-mediated transport; carrier-mediated ...
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and aging, helping to delay senescence and promote cellular repair. Metformin boosts insulin sensitivity, reduces oxidative stress, and may improve mitochondrial function and slow age-related cellular decline. It is also often used to help infertility problems like PCOS that hinge on insulin resistance...
It covers the advantages of the composite hydrogels, EV and hydrogel characteristics, synthesis methods, and the impact of the composite hydrogels on wound healing. The discussion includes existing challenges, future research directions, and implications in the field....