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品系基本信息 细胞系名称 KPC 目录号 NM-YD04 品系描述 KPC 细胞是来源于三基因阳性小鼠(Pdx1-cre/LSL-Kras G12D/P53(R172H))自发胰腺癌肿瘤,在 C57BL/6 小鼠皮下接种后,能正常成瘤。 品系状态 成瘤性验证完成 *使用本品系发表的文献需注明: KPC cell line (Cat. NO. NM-YD04) was purchased from...
图1制备KPC小鼠模型 CDX(cellline derived xenograft)人胰腺癌细胞系在免疫缺陷鼠的原位移植瘤 将已建立的人胰腺癌细胞系作为移植物,植入免疫缺陷小鼠制作模型,测试药物安全性和有效性,用于药物筛选、药代动力学和药效学评估及毒性检测。由于人胰腺癌细胞系经过人工多代培养纯化,无...
品系基本信息 细胞系名称 KPC(R270H) 目录号 NM-YD11 品系描述 Trp53(R270H-flox)/Kras(LSL-G12D)/Tg(Pdx1-cre)小鼠胰腺癌细胞系 品系状态 构建完成 *使用本品系发表的文献需注明: KPC(R270H) cell line (Cat. NO. NM-YD11) was purchased from Shanghai Model Organisms Center, Inc.. ...
test was used to assess the inhibitory effect on cell migration from KPC -L006.Cell apoptosis on AnnexinV /PI assay was observed.Measurement of the expression level of apoptosis -related protein was processed by western blotting.After the treatment of KPC -L006,the activity of PC9cell line ...
In order to enable real-time monitoring of orthotopically engrafted tumor growth using optical imaging, we generated and characterized a firefly luciferase (Luc) expressing model via lentivirus transfection of the syngeneic cell line derived from parental KPC MuPrime tumors.Results: We successfully ...
Capsules can prevent cell adherence and phagocytosis, thereby enhancing virulence. Furthermore, the loss of the hypermucoviscous phenotype is associated with reduced virulence [18, 22,23,24]. The emergence of carbapenem-resistant HMKP (CR-HMKP) has attracted attention recently [25]. However, ...
TN, Rhee C, Klompas M, Dekker JP, Powers JH, Suffredini AF, Hooper DC, Fridkin S, Danner RL (2018) Difficult-to-treat resistance in gram-negative bacteremia at 173 US hospitals: Retrospective cohort analysis of prevalence, predictors, and outcome of resistance to all first-line agents. ...
moniaeATCCBAA-1705strain.thenitwasclonedintopET-22b(+)vectorandtransformedintothehostcellsE. coliBL21(DE3) strain.TheKPC一2proteinwasexpressedfollowingIPTGinduction,andwaspurifiedbyaffinity chromatography.Thepurityofpurified proteins weredetermined by SDS-PAGE.Explore andBioTekGen5 was usedtoinvestigateitsanti...
Delphi KPC QCI