26、在小鼠的基因组中,klrg1基因(ncbi gene id:50928,uniprot id:o88713,位于6号染色体nc_000072.7的第122247555至122259792位)包含5个外显子,即外显子1、外显子2、外显子3、外显子4和外显子5。基于转录本nm_016970.1及其编码蛋白np_058666.1(seqid no:1)的核苷酸序列和氨基酸序列中每个外显子对应位置如表2...
基因又名: 2F1; CLEC15A; MAFA; MAFA-2F1; MAFA-L;MAFA-LIKE Gene ID: 10219 种属 Homo sapiens DNA序列编号: NM_001329099.2 DNA描述 Homo sapiens killer cell lectin like receptor G1 (KLRG1), transcript variant 1, mRNA DNA大小: 1401 bp DNA编码区: atgactgacagtgttatttattccatgttagagttgcctacg...
基因简称(symbol) KLRG1 [HGNC] [GeneCards] [NCBI] 基因种类(locus group) protein-coding gene 同源简称(alias symbol) MAFA|2F1|MAFA-L|CLEC15A 基因家族代码(gene_family_id) 494|621 [HGNC] [GenScript] omim代码 604874 entrez码 10219 [Vega] ensembl基因码 ENSG00000139187 [Ensembl] ...
SV40 polyadenylation signals downstream of the EGFP gene direct proper processing of the 3' end of the EGFP mRNA. The vector backbone also contains an SV40 origin for replication in mammalian cells expressing the SV40 T antigen. A neomycin-resistance cassette (Neor ), consisting of the SV40 ...
Thus, mice specifically lacking induction of pTregs (via deletion of the CNS1 enhancer region of the Foxp3 gene, which is required for TGFβ-mediated pTreg induction) develop inflammation of the intestine and lung (Josefowicz et al., 2012). Similarly, mouse models where pTregs are ...
Banh, C.et al. (2009) Blood114:5299. Long Name Killer Cell Lectin-like Receptor Subfamily G Member 1 Entrez Gene IDs 10219 (Human); 50928 (Mouse); 58975 (Rat) Alternate Names 2F1; CLEC15A; CLEC15AMAFA-LIKE; C-type lectin domain family 15 member A; C-type lectin domain family 15...
Thus, KLRG1-mediated signal might have a role in preventing autoimmunity, increasing the activation threshold of NK cells.2 KLRG1 gene also, emerged as a disease susceptibility gene for SLE in four different ethnic groups.3 Objectives The aim of this study was to characterize KLRG1 expression on...
Killer Cell Lectin-like Receptor Subfamily G Member 1 Entrez Gene IDs 10219 (Human); 50928 (Mouse); 58975 (Rat) Alternate Names 2F1; CLEC15A; CLEC15AMAFA-LIKE; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer...
The location and length of theKLRG1gene and the structure of the KLRG1 protein differ between mice and humans (Table1). First, theKLRG1gene is located on chromosome 6 in mice and chromosome 12 in humans and is transcribed into mRNA by a promoter, followed by selective splicing ofKLRG1mRNAs ...