Rattus norvegicus killer cell lectin-like receptor subfamily C,member 1 (Klrc1), mRNA. 基因ID: 29683 序列: atgagtaatgatcgagtcacctatgcagaactgaatgtggccaagaactcaaggtaccagcacaacaaaccaaggggcagtcgcagctccatttcagtaatagagcaggaaatcgtttatgcggatttcagctttaaaaatccttctcaagagcagacccggatctgcagggattgc...
NKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this proteins is characteri...
NKG2A inhibits invariant NKT cell activation in hepatic injury. Activation of invariant NKT (iNKT) cells in the liver is generally regarded as the critical step for Con A-induced hepatitis, and the role of NK cell recep... T Kawamura,K Takeda,H Kaneda,... - 《Journal of Immunology》 被...
按照Human T Cell Nucleofector Kit(Lonza)的操作手册,将载有sgRNA寡聚核苷酸的质粒与序列为SEQ ID NO.76的Cas9质粒(结构如图2所示)混匀,共转染细胞。 5.用T7EN1酶切检测和流式细胞术检测确认NKG2A/KLRC1基因已经被敲除。 更进一步的,同时利用一对相邻(在人NKG2A/KLRC1基因上的靶向起始位点相距0-200bp)的sgR...
Haematologic Technologies,Haematologic Technologies Inc,Hyglos,IBL,immunodx,Immunostep,ImmunoVision,innovagen,iris-biotech,jackson抗体,lifecore,LSBIO,macrocyclics,medkoo biosciences,NEB,NIBSC,NIST标准品,omega试剂盒,Percipio Biosciences,PhosphoSolution,promocell,sigma,thermo,TLC标准品,tocris,试剂盒,细胞株,重组...
(aa 94-244), mouse NKG2A shares 71% and 41% aa sequence identity with rat and human NKG2A, respectively. An isoform lacking aa 98-114 has been described. NKG2A associates with CD94 and is coexpressed on NK cells and some activated T cell populations. The NKG2A/CD94 complex delivers ...
NKG2, also known as NKG2A(CD159A), contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this proteins is characterized by th...
The NKG2A/CD94 receptor interaction with the HLA-E ligand results in phosphorylation of NKG2A's immunoreceptor tyrosine-based inhibition motifs (ITIMs), causing suppression of activating signals from immunoreceptor tyrosine-based activation motif (ITAM)- containing T cell receptors (TCR) or other ...
NKG2A belongs to a group of natural killer (NK) cell inhibitor receptors (IRs) which includes killer immunoglobulin receptors (KIRs), lymphocyte activation gene-3 (LAG-3), T cell immunoreceptor with Ig and ITIM domains (TIGIT), programmed death ligand-1 (PD-1), and T cell immunoglobulin ...
DNA描述 Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 1, mRNA DNA大小: 1436 bp DNA编码区: atggataaccaaggagtaatctactcagacctgaatctgcccccaaacccaaagaggcag caacgaaaacctaaaggcaataaaaactccattttagcaactgaacaggaaataacctat gcggaattaaaccttcaaaaagcttctcaggattttcaagggaatgacaaaa...