Immunostaining demonstrated most of the infiltrating cells to be IgA, kappa, CD38, and CD138 positive. Immunofixation blood test revealed IgA kappa-type M protein; however, bone marrow abnormalities or lymph node enlargements on examination or imaging, respectively, were not observed. ...
An alternative approach is to identify other phenotypic abnormalities (eg, bcl-2 staining of CD10 positive B-cells in FL) (see Fig. 5) [22]. Sign in to download hi-res image Fig. 6. Plasma cell neoplasm. (A) Plasma cells identified with staining for CD138 are abnormally CD19 ...
Plasma NF-κB (p = 0.7) and IκB-α (p = 0.8) expression was similar between HIV positive and HIV negative pregnant women, irrespective of pregnancy type. Conclusion: This study demonstrates decreased plasma NF-κB and IκB-α expression in preeclampsia compared to normotensive pregnant women ...
Immunoglobulin secreted by B cells and plasma cells is mainly composed of heavy chain and light chain, and the latter can be categorized into light chain kappa (K) and lambda (L). The concentration of normal human serum kappa light chain is about two times of that of lambda light chain. ...
(Jackson ImmunoResearch), subsequently fixed with 1% paraformaldehyde, and processed by flow cytometry using a BD FACS-Canto II. Data was analyzed using FlowJo software. Percent binding was calculated as the percentage of PE-positive cells with background (mAb binding to mock transfected cells) ...
Methods: To answer this question, we examined the behavioral consequences of targeted ablation of GFAP-positive cells in the PFC in baseline and stress conditions on anhedonia, anxiety and helplessness. To achieve this goal, we developed an approach adapted from cre/loxP system strategy in which ...
Cells positive for either the kappa opioid receptor or both the kappa opioid receptor and preprodynorphin were restricted to the vasopressin expressing neuronal population and not found in the oxytocin expressing neuronal population. The kappa opioid receptor and dynorphin were examined in the posterior...
A positive temperature-sensitive hydrogel has an upper critical solution temperature (UCST), i.e., these contract upon cooling below the UCST. Negative temperature-sensitive hydrogels have a lower critical solution temperature (LCST), i.e., these contract upon heating above the LCST.79,80 This ...
Upon treatment with lipopolysaccharide (LPS), primary B cells proliferate and differentiate into plasma cells with concomitant up-regulation of immunoglobu... KB Meyer - 《European Journal of Immunology》 被引量: 25发表: 2015年 Requirement of NEMO/IKKγ for effective expansion of KRAS-induced pre...
KAPPA OPIOID RECEPTOR mRNA原位杂交试剂盒原位杂交是在一定生物结构基础之上的核酸杂交。这种结构基础可以是一条染色体;一个细菌;更大结构基础是细胞和组织。基本原理是两条核苷酸单链片段,在适宜的条件下,通过氢键结合,形成DNA-DNA、DNA-RNA或RNA-RNA 双键分子,应用带有标记的(有放射性同位素,如3H、35S、32P、荧光...