Gastric Kappa-Restricted Plasma-Cell Neoplasm: Diagnosed on Routine Endoscopic Evaluation: 929Jafri, RizwanSapp, AbbyNawaz, MustafaYarbrough, AlexOfficial journal of the American College of Gastroenterology | ACG
Fig. 6.Plasma cell neoplasm. (A) Plasma cells identified with staining for CD138 are abnormally CD19 negative, and demonstrate cytoplasmic lambda immunoglobulin light chain restriction (B, C). View article Isotype Defects Mirjamvan der Burg, ...CharlotteCunningham-Rundles, inStiehm's Immune Defici...
The presence of both kappa- and lambda-light chain-restricted B-cell populations in B-cell lymphomas, including MALT lymphoma, is an unusual findings [16]. Edinger et al. reported 2 other examples of primary cutaneous marginal zone lymphomas that express both kappa- and lambda-light chain-...
The infiltrated plasma cells were Kappa light chain-restricted, but did not show the immunophenotypes for a plasma cell neoplasm. In addition, the patient developed Kappa-restricted plasma cell myeloma 2 years later. The patient was followed up for 8 years, and her breast lesion did not show ...