Isocitrate dehydrogenase mutations in gliomas. Neuro-Oncol 2015; 18: 16-26.Waitkus M.S., Diplas B.H., Yan H. Isocitrate dehydrogenase mutations in gliomas. Neuro. Oncol. 2015 doi: 10.1093/neuonc/nov136. [ Cross Ref ]Waitkus, M.S.; Diplas, B.H.; Yan, H. Isocitrate dehydrogenase ...
Schiff D and Purow BW: Neuro‑oncology: isocitrate dehy- drogenase mutations in low‑grade gliomas. Nat Rev Neurol 5: 303‑304, 2009.DavidSchiff, Benjamin W.Purow. (2009) Neuro-oncology: Isocitrate dehydrogenase mutations in low-grade gliomas. Nature Reviews Neurology 5 , 303-304 /...
Here we describe the first application of a miniature mass spectrometer (MS) to the determination of IDH mutation status in gliomas intraoperatively. The instrumentation was modified to be compatible with use in the operating room. Tandem MS was performed on the oncometabolite, 2-hydroxyglutarate, ...
Clinico-neuropathological features of isocitrate dehydrogenase 2 gene mutations in lower-grade gliomas Chin Med J (Engl), 132 (24) (2019), pp. 2920-2926 CrossrefView in ScopusGoogle Scholar 22 L. Poetsch, C. Bronnimann, H. Loiseau, et al. Characteristics of IDH-mutant gliomas with non...
Isocitrate dehydrogenase mutations in gliomas. Neuro Oncol 18, 16–26 (2016). 33. Hartong, D. T. et al. Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle. Nat Genet 40, 1230–1234 (2008). 34. Zeng, L. et al. Aberrant IDH3alpha ...
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism J Natl Cancer Inst, 102 (2010), pp. 932-941 CrossrefView in ScopusGoogle Scholar 11 L. Dang, D.W. White, S. Gross, B.D. Bennett, M.A. Bittinger, E.M. Driggers, V.R. Fantin...
A population-based study of low-grade gliomas and mutated isocitrate dehydrogenase 1 (IDH1) Low-grade gliomas (LGG) have a slow growth rate, but transformations into malignant gliomas with a rapid deterioration occur in many patients. The aim of t... RH Dahlrot,BW Kristensen,J Hjelmborg… ...
IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders Frequent mutations in the isocitrate dehydrogenase 1 and 2 genes (IDH1 and IDH2) have been identified in gliomas and acute myeloid leukemia (AML). Our aim .....
Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome ...
Isocitrate dehydrogenase mutations in gliomas. Neuro Oncol 18, 16–26 (2016). 13. Stoddard, B. L., Dean, A. & Koshland, D. E. Jr. Structure of isocitrate dehydrogenase with isocitrate, nicotinamide adenine dinucleotide phosphate, and calcium at 2.5-A resolution: a pseudo-Michaelis ternary ...