Prostate cancer is a common multiple malignant tumor occurring in males. Prostate cancer mortality is the 2nd most common of all tumor types in Western countries and the mortality of morbidity is...
And as abnormal cells continue to accumulate, normal cells die and a tumor forms. That tumor can grow and spread to nearby tissue, and those abnormal cells can also spread to other parts of the body. What are the signs and symptoms of prostate cancer? Prostate cancer usually doesn’t ...
Prostate cancer is a type of reproductive cancer that generally affects men over the age of 65 years. It is one of the most common types of male reproductive cancer and each year, around 175,000 men in the U.S. alone will be diagnosed with the disease....
Aggressive multimodality therapy for patients with locally advanced esophageal cancer: is there a role for amifostine? Most patients with locally advanced esophageal cancer die from their disease, despite complete surgical extirpation of tumor or institution of aggressive, multimodality treatment. Nevertheless...
Older patients who are diagnosed when they're already in poor health face the same dilemma: doctors have to decide whether the negative side effects from treatment outweigh the risk of the tumor spreading and becoming symptomatic. Prostate cancer symptoms include trouble urinating, blood in the urin...
Tumors can be classified as either benign or malignant depending on how dangerous they are. Answer and Explanation: The correct answer is (d) Both (b) and (c). Metastatic cancer occurs when a primary tumor, or mass of cancer cells, spreads to other ...
Organoid allelic series and tumor phenotype characterization We sought to develop a platform to interrogate prostate cancer drivers rapidly and comprehensively at larger scale compared to traditional genetically engineered mouse models (GEMMs), focusing on the need to dynamically model the PRAD-to-NEPC tr...
After the introduction of serum PSA over 20 years ago as a tumor marker for prostate cancer, controversy regarding PSA and prostate cancer screening still abounds. First, who should be screened? Second, does screening affect mortality? Third, serum PSA used for screening has a low specificity (...
Prostate cancer disseminates initially and primarily to regional lymph nodes. However, the nature of interactions between tumor cells and lymphatic endothelial cells (LEC) is poorly understood. In the current study, we have isolated prostate LECs and developed a series of two-dimensional and three-...
Therefore, we propose a new mechanism in which Smad3/Sox5/Twist1 promotes EMT and contributes to PCa progression. Similar content being viewed by others TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating...