title: delineating the effects of tumor therapies on prostate cancer using small animal imaging technologies principal investigator JS Lewis 被引量: 0发表: 2019年 High-resolution optical imaging of functional brain architecture in the awake monkey Optical imaging of the functional architecture of cortex...
(Box 1). The major events relevant in tumorigenesis – proliferation, survival, and hematogenous spread of the malignant cells – are all dependent on specific combinations of cell types andsoluble factorspresent in the micro-environmental niches [6,8,9]. Being a heterogenic and dynamically ...
Prostate cancer is the second most common malignancy in men worldwide and consists of a mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor microenvironment, we perform single-cell RNA-sequencing on prostate biopsies, prostatectomy specimens, and patient-derived organo...
Novara G, Galfano A, Secco S, Ficarra V, Artibani W (2009) Impact of surgical and medical castration on serum testosterone level in prostate cancer patients. Urol Int 82(3):249–255 Article CAS PubMed Google Scholar Vachani C (2018) Oncolink. Hormone therapy: the basics. https://www...
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Targeting Multiple Signaling Pathways as a Strategy for Managing Prostate Cancer: Multifocal Signal Modulation Therapy The aberrant behavior of cancer reflects upregulation of certain oncogenic signaling pathways that promote proliferation, inhibit apoptosis, and enable the... McCarty,F M. - 《Integrative...
Dysfunction of invariant natural killer T (iNKT) cells contributes to immune resistance of tumors. Most mechanistic studies focus on their static functional status before or after activation, not considering motility as an important characteristic for an
We assessed the impact of tumor volume, tumor volume ratio (tumor volume-to-prostate volume), surgical experience and type of nerve sparing procedure on biochemical recurrence after laparoscopic radical prostatectomy. Of 1,600 laparoscopic radical prostatectomies performed between March 1999 and May 200...
Evidence from physical sciences in oncology increasingly suggests that the interplay between the biophysical tumor microenvironment and genetic regulation has significant impact on tumor progression. Especially, tumor cells and the associated stromal cel
This includes cells derived from a range of hematological malignancies47 and breast, prostate, lung, and colon cancer.42, 48, 62 Therefore, it is of particular interest that the member of the ADAM family reported to shed cell-associated neural adhesion molecules such as L1 may be relevant to...