Based on the lipoate redox state, PfLipL1 either functions as a canonical lipoate ligase or as a lipoate activating enzyme which works in conjunction with PfLipL2. We demonstrate that PfLipL2 is a lipoyltransferase and is a member of a novel clade of lipoate attachment enzymes. We show...
Acyl-CoA Synthetase (ACOS) genes are related to 4-coumarate: CoA ligase (4CL) but have distinct functions. The Arabidopsis thaiiana ACOS5 protein is in cla... ASC De,SS Kim,S Koch,... - 《Plant Cell》 被引量: 403发表: 2009年 ...
To our knowledge, AmiACp is the first example of an enzyme possessing amidase and DD-CPase activity. Moreover, our study revealed that AmiA is a so far unknown target of penicillin in Chlamydiaceae, besides the PBPs PBP2, PBP3 and PBP6. It is not known whether homologous amidases from...
Since E3 ligase plays an indispensable role in the ubiquitination process, we explored the involvement of this enzyme in GSDMD ubiquitination. Analysis of the UbiBrowser database revealed that SYVN1 is one of the most important E3 ligases involved in GSDMD ubiquitination (Supplementary Fig. 1A). HE...
An increase in USP18 expression during muscle cell differentiation is independent of its role in the interferon type 1 stimulated response. During normal muscle cell differentiation, USP18 accumulates in the cell nucleus regulating multiple cellular processes, including proliferation, differentiation initiatio...
Shibuya N, Minami E (2002) EL5, a rice N-acetylchitooligosaccharide elicitor-responsive RING-H2 finger protein, is a ubiquitin ligase which functions in vitro in co-operation with an elicitor-responsive ubiquitin-conjugating enzyme, OsUB... R Takai,N Matsuda,A Nakano,... - 《Plant Journal》...
The DNA ligase from Thermus thermophilus (Tth DNA ligase) seals single-strand breaks (nicks) in DNA duplex substrates. The specificity and thermostability ... J Luo,DE Bergstrom,B Francis - 《Nucleic Acids Research》 被引量: 485发表: 1996年 Insights into DNA polymerization mechanisms from struct...
Molecular cloning and sequencing of human palmitoyl-CoA ligase and its tissue specific expression Mol. Cell. Biochem., 151 (1995), pp. 77-81 View in ScopusGoogle Scholar 15 A. Harington, E. Schwarz, P.P. Slonimski, C.J. Herbert Subcellular relocalization of a long-chain fatty acid CoA ...
Here, we show that BrtB is an O-alkylating enzyme that catalyzes the esterification of free (non-activated) fatty acids with the chlorinated positions found in the bartolosides, generating a diversity of fatty acid-bartoloside esters (Fig. 1g)....
Alpha globin inhibition of eNOS-derived NO signaling necessarily requires O2, as both eNOS enzyme activity and NO scavenging and subsequent transformation to NO3– by alpha globin require O2. Conversely, endothelial alpha globin (as with erythrocyte hemoglobin) must be deoxygenated to act as a ...