Betteridge D: Cholesterol is the major atherogenic lipid in NIDDM. Diabetes Metab Rev 13: 99-104, 1997.Betteridge D. Cholesterol is the major atherogenic lipid in NIDDM[J]. Diabetes Metab Rev,1997,13:99.Betteridge D.Cholesterol is the major atherogenic lipid in NIDDM.Diabetes Metabolism Reviews...
Lipid raft-based membrane order is important for antigen-specific clonal expansion of CD4+ T lymphocytes. Background Lipid rafts are cholesterol and saturated lipid-rich, nanometer sized membrane domains that are hypothesized to play an important role in compar... Schieffer,Daniel,Naware,... - ...
To prepare pyranine-loaded liposomes, a lipid (2 mg POPC, 1 mg POPG, and 1 mg cholesterol) in a chloroform suspension was dried in a round-bottom flask under a stream of nitrogen. The lipid was then resuspended in a buffer (100 mM KCl, 20 mM MES, 20 mM MOPS, 20 mM Tricine ...
L. Cholesterol provides nonsacrificial protection of membrane lipids from chemical damage at air–water interface. Proc. Natl Acad. Sci. USA 115, 3255–3260 (2018). Article ADS CAS PubMed PubMed Central Google Scholar McLean, L. R. & Hagaman, K. A. Effect of lipid physical state on ...
Although they are more ordered and closely packed, they still have the ability to float freely within the membrane bilayer. The most commonly used drugs to control the formation and function of lipid drafts are nystatin and filipin which sequester cholesterol, MβCD which is used to deplete ...
Cholesterol mobilization from hepatic lipid droplets during endotoxemia is altered in obese ob/ob mice Navarro‑Imaz H, Rueda Y and Fresnedo O: Cholesterol mobilization from hepatic lipid droplets during endotoxemia is altered in obese ob/ob mice... L Arisqueta,H Navarro-Imaz,Y Rueda,... -...
Cellular cholesterol can be metabolized to its fatty acid esters, cholesteryl esters (CEs), to be stored in lipid droplets (LDs). With triacylglycerols (TGs), CEs represent the main neutral lipids in LDs. However, while TG melts at ~4 °C, CE melts at
The jejunal and ileal Abcg5 and Abcg8 played a major regulatory role in response to high dietary cholesterol and were more sensitive in the regulation of Ch absorption when compared with sitostanol absorption. These results, combined with different sterol uptake rates, suggest that the absorption...
The major neutral lipid found in the HG of the mouse is ADG with lower levels of phospholipid and free cholesterol. As indicated in Fig. 2 and Table I, the SCD1−/− mice have a deficiency in ADG and C20:1n-9; the main monounsaturated fatty acid in ADG was reduced by greater ...
Fig. 5: Depletion of PI(4,5)P2decreases the plasma membrane cholesterol. a, bDetection of cholesterol using recombinant mCherry-D4 protein (D4) in GFP-, Lyn-INPP5Ewt-GFP (INPP5E WT)-, and Lyn-INPP5Emt-GFP (INPP5E MT)-expressing HaCaT cellsa. Quantification of the plasma membrane...