Pamela M. SmithJohn Wiley & Sons, LtdPhilpott, C., and P. Smith, 2013 The iron starvation response in Saccharomyces cerevisiae, Metals in Cells, edited by R. Scott, and V. C. Culotta The Encyclopedia of Inorganic Biochemistry. John Wiley & Sons, New York....
elegans in response to mitochondrial stress in a pdr-1/Parkin-, pink-1/Pink-, and dct-1/Bnip3-dependent manner. The induction of mitophagy is part of a hypoxia-like, iron starvation response triggered upon frataxin depletion and causally involved in animal lifespan extension. We also ...
Iron is an essential cofactor, but it is also toxic at high levels. In Schizosaccharomyces pombe, the sensor glutaredoxin Grx4 guides the activity of the repressors Php4 and Fep1 to mediate a complex transcriptional response to iron deprivation: activation of Php4 and inactivation of Fep1 leads...
NHE9 Expression in hBMVECs Activates Iron Starvation Response to Promote Iron Uptake Next, we evaluated the hBMVECs response to an increase in NHE9 expression. However, instead of using paracrine signals from iron-deficient astrocytes as the stimulants, we engineered lentiviral-mediated expression of...
In contrast, production of filamentous hemagglutinin is reduced in iron-depleted Bordetella. Thus, B. bronchiseptica controls the expression of virulence genes in response to iron starvation. 展开 关键词: Bordetella bronchiseptica type III secretion system iron starvation ...
Genes involved in iron (Fe) acquisition often are regulated in response to the local availability of Fe. In many bacteria, Fe-dependent responsiveness is m... Amy,E,Kirby,... - 《Infection & Immunity》 被引量: 37发表: 2004年 Taishan Pinus massoniana pollen polysaccharides promote immune res...
In Saccharomyces cerevisiae, expression of the transcriptional activator GCN4 increases at the translational level in response to starvation for an amino a... R Cuesta,AG Hinnebusch,M Tamame - 《Genetics》 被引量: 191发表: 1998年 加载更多来源...
Regulation of the isc operon is mediated by IscR, whereas the suf operon requires OxyR and IHF for the response to oxidative stress and Fur for induction by iron starvation. Simultaneous deletion of iscS and most suf genes is synthetically lethal. However, although the suf and isc operons ...
The ferric uptake regulator (Fur) plays a central role in this response and also controls other regulatory genes, such as pvdS , which encodes an alternative sigma factor. This circuit leads to a hierarchical cascade of direct and indirect iron regulation. We...
Transcriptional profiling of the iron starvation response in Bordetella pertussis provides new insights into siderophore utilization and virulence gene expression. J Bacteriol. 2011;193:4798-812.Brickman TJ, Cummings CA, Liew SY, Relman DA, Armstrong SK. 2011. Transcriptional profiling of the iron ...