iron‐sparing responsefungal iron‐dependent CCAAT‐binding factorsiron‐regulatory GATA‐type transcription factorsWhen iron load exceeds that needed by fission and filamentous yeasts, iron-regulatory GATA-type transcription factors repress genes encoding iron acquisition systems. In contrast, under iron ...
et al. The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins. Proc. Natl. Acad. Sci. USA 105, 11927–11932 (2008). Article ADS CAS Google Scholar Smaldone, G. T. et al. A global investigation of the Bacillus subtilis ...
these increases may also suggest a greater reliance on iron recycling or releasing stored iron to support growth in the short-term. Also in response to increased CO2at Experiment 1,centric diatoms increased transcript expression of a CREG-like gene (cellular repressor of E1...
Gaballa A, Antelmann H, Aguilar C, Khakh SK, Song KB, Smaldone GT, Helmann JD (2008) The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins. Proc Natl Acad Sci U S A 105:11927–11932 Article CAS PubMed PubMed Central ...
The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins Regulation of bacterial iron homeostasis is often controlled by the iron-sensing ferric uptake repressor (Fur). The Bacillus subtilis Fur protein acts as a... A Gaballa,H Antelm...
Transcriptional response to the absence of VIT The finding that VIT appears regulated by iron led us to examine how the transcriptome changes in the absence of VIT and correct iron storage. RNAseq was performed on the parental and ΔVIT strains in triplicate. We confirmed that none of the re...
(Fur) protein as master regulator and at least two subsidiary regulatory systems. The most significant of these is an iron-sparing/prioritization response controlled by the small RNA FsrA and three auxiliary proteins (FbpABC). In addition, the bacillibactin uptake system is transcriptionally ...
International Journal of Molecular Sciences Review Targeting the Iron-Response Elements of the mRNAs for the Alzheimer's Amyloid Precursor Protein and Ferritin to Treat Acute Lead and Manganese Neurotoxicity Jack T. Rogers 1,*, Ning Xia 2, Angela Wong 1, Rachit Bakshi 2 and Catherine M. Cahill...
It effectively displayed antiproliferative activity against four cancer cell lines: A549 (IC50 = 2.4 μM), MiaPaCa (IC50 = 9.5 μM), A2058 (IC50 = 6.5 μM), and HT-29 (IC50 = 0.95 μM), while sparing normal cells. Importantly, their findings provided preliminary evidence supporting the...
Like CIS, selective T2 hypointensity was found in the caudate nucleus of pediatric MS patients with a sparing of other deep GM structures (Ceccarelli et al., 2011). Furthermore, despite their favorable clinical course and the lower overall brain tissue damage, similar T2 intensity was found in...