Iron deposition in liver was significantly reduced in groups supplemented with iron peptide complex when compared with the iron sulfate-supplemented groups (30 and 60 mg Fe/kg). A significant reduction of iron deposition in spleen was also shown in groups supplemented with iron-peptide complex (10...
Erythro- cyte-aniline interaction leads to their accumulation and iron deposition in rat spleen. J. Toxicol. Environ. Health 44, 415 - 421.Khan, M. F., Kaphalia, B. S., and Ansari, G. A. S. (1995a). Erythrocyte-aniline interactions leads to their accumulation and iron deposition in...
Although iron deficiency occurred commonly in the elderly, accumulation of iron in certain organs and tissues was observed, including brain, liver, spleen, kidney, and skeletal muscles, indicating malfunction of iron homeostasis [5, 22]. Iron deposition in senescent cells was observed, which was ...
Rapid induction of iron deposition in spleen and liver with an iron-fructose chelate. The dietary effectiveness of an iron-fructose chelate was compared with FeSO4 using the criteria of total iron analyses and histologic staining technics on... C Stitt,PJ Charley,EM Butt,... - 《Proceedings of...
Appreciably elevated hepatic iron concentrations were associated with heavy iron deposition in both hepatocytes and macrophages, and either portal fibrosis or cirrhosis. All were negative for the C282Y mutation. Very high concentrations were uncommon in subjects dying in hospital. Concentrations of iron ...
Specific Hemosiderin Deposition in Spleen Induced by a Low Dose of Cisplatin: Altered Iron Metabolism and Its Implication as an Acute Hemosiderin Formation Model. Curr. Drug Metab. 2010, 11, 507–515. [Google Scholar] [CrossRef] [PubMed] Makhdoumi, P.; Abnous, K.; Mehri, S.; Etemad,...
nevertheless, the analyses of visceral organs and biochemistry demonstrated normal results, except for time-dependent iron deposition in the spleen. Therefore, compared with conventional ISs, bioabsorbable iron-based ISs exhibit higher initial mechanical strength. Although iron-based ISs demonstrate high ...
These observations may explain the variable correlation observed between the severity of myocardial iron deposition and that of cardiac fibrosis.71, 72 The Impact of Iron-Chelating Therapy on Cardiac Disease and Survival The beneficial effects of deferoxamine therapy on survival and cardiac disease in ...
IRPs bind to the iron-response element (IRE) of their target mRNAs, balancing iron uptake and deposition at the posttranscriptional levels. However, IRP/IRE-dependent iron regulation in adipocytes is largely unknown. We hypothesized that iron demands are higher in brown/beige adipocytes than white...
In the pathology of neuroinflammation, different types of glial cells can regulate neuronal iron deposition in a positive or negative manner, influencing the process of ferroptosis. Iron overload can activate microglia and astrocytes [178]. Inflammatory cytokines released by activated microglia and astroc...