ReviewIP 3 -dependent calcium-induced calcium release mediates bidirectionalcalcium waves in neurones: functional implications for synaptic plasticityJ.-G. Barbara *Laboratoire de Neurobiologie des Processus Adaptatifs, UMR CNRS 7102, 7 Quai Saint Bernard, Case 8, 75252 Paris Cedex 5, FranceReceived...
末次给药2 h后,观察大鼠一般行为状况,检测脑干听觉诱发电位(auditory brainstem response,ABR)和血清及脑干组织胆红素含量;HE染色观察耳蜗核组织病理变化;免疫组化染色法观察耳蜗核组织钙素(calcium,CaM)活性;蛋白免疫印迹法(Western blotting...
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Fractalkine has also been shown to increase cytosolic calcium ([Ca2+]i) in microglia. MATERIAL AND METHODS Based on the characteristics of CX3CR1, a G protein-coupled receptor, we explored the role of inositol 1,4,5-trisphosphate (IP3) signaling in fractalkine-induced inflammatory response in...
Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites. The second messenger inositol-1,4,5-trisphosphate (InsP3) releases Ca2+ from intracellular Ca2+ stores by activating specific receptors on the membranes of... Finch,EA,Augustine,GJ - 《Nature》 被引量: 907...
Prostate cancer (PrCa) progression and mortality are associated with calcium metabolism, parathyroid hormone level, and vitamin D level. However, the lack of comprehensive understanding on the molecular rationale of calcium intake, serum homeostasis, and
The size of the endoplasmic reticulum (ER) calcium pool and the number of IP3 receptors per cell are decreased in response to stimuli that activate NF-κ B and are increased when NF-κ B activity is suppressed. The selective antagonism of IP3 receptors blocks apoptosis in RelA-...
CONCLUSION: Our results indicate that altered calcium response to CCK-8 in diabetic acini might be associated with a post-CCK receptor defect including the changes in IP formation, type III IP3R protein expression, and phosphorylation of type III IP3R protein. 展开 关键词: Keywords diabetic ...
Regulation of slow wave frequency by IP[sub 3]-sensitive calcium release in the murine small intestine. Examines the regulation of slow wave frequency by inositol 1,4,5,-triphosphate-sensitive calcium release in the murine small intestine. Pharmacological mod... Malysz,John,Huizinga,... - 《...