Importantly, the protein level of PPP3CC negatively correlates with the cellular level of IP3, suggesting a regulatory role of PPP3CC in the IP3-Ca2+ signaling pathway. 展开 关键词: INOSITOL 1 5-TRISPHOSPHATE KAWASAKI-DISEASE SCHIZOPHRENIA SUSCEPTIBILITY ACTIVATION CA2 TRISPHOSPHATE EXPRESSION ...
In addition there are RyR-like channels activated by cADPR (cyclic ADP-ribose), Sphingosine and a distinct Ca2+-release pathway activated by NAADP (Nicotinic Acid Adenine Dinucleotide Phosphate). Within Ca2+-storing organelles, Ca2+ ions are bound to specialized Ca2+-buffering proteins. These ...
distinct Ca2+-release pathway activated by NAADP (Nicotinic ADP-ribose), Sphingosine and a distinct Ca2+-release pathway activated by NAADP (Nicotinic Acid Adenine Dinucleotide Phosphate). Within Ca2+-storing organelles, Ca2+ ions ...
IP3通路可以引起细胞内肌浆网和内质网钙库Ca2+通过钙池操纵的钙通道流入细胞质,从而改变细胞内的Ca2+浓度[6],IP3通路改变细胞内的Ca2+浓度可以引起一系列的生物学效应。目前有关IP3通路的研究主要集中在肌肉、血管和心脏上,在脂肪代谢上的研究很少。为此,本研究用IP3通路的激动剂(去甲肾上腺素(NE))和抑制剂(肝素...
In the present study, we investigated whether the IP3 signaling pathway operates in intact Plasmodium falciparum, the major disease-causing human malaria parasite. P. falciparum-infected red blood cells (RBCs) in the trophozoite stage were simultaneously loaded with the Ca2+ indicator Fluo-4/AM ...
细胞信号通路ppt细胞信号通路大全上下细胞信号通路ppt ip3_pathway.ppt,GP C R C N IP3 Pathway C D 1 9 Ag Iga Iga I gb I gb L A T TCR-CD3 Complex Growth Factor Receptor CaCn Complex MEF2 p300 CREB CBP Growth Factors Gene Expression NFAT I P 3 R Ca2+ Ga Gb Gg
Localized IP3-evoked Ca2+ release activates a K+ current in primary vagal sensory neurons. J Neurophysiol 91, 2344-52... RE Hoesch,D Weinreich,JPY Kao - 《Journal of Neurophysiology》 被引量: 20发表: 2004年 localized ip 3 -evoked ca 2 release activates a k current in primary vagal senso...
However, MCU-dependent mitochondrial sequestration of Ca2+ entering through the SOCE pathway was essential to prevent slow deactivation of SOCE. Our findings show a stimulus-specific contribution of mitochondrial Ca2+ uptake to the SOCE machinery, likely through a role in shaping cytosolic Ca2+ micro...
Microscopic properties of elementary Ca2+ release sites in non-excitable cells Curr. Biol., 10 (2000), pp. 8-15 View PDFView articleView in ScopusGoogle Scholar Thurley and Falcke, 2011 K. Thurley, M. Falcke Derivation of Ca2+ signals from puff properties reveals that pathway function is ro...