Importantly, the protein level of PPP3CC negatively correlates with the cellular level of IP3, suggesting a regulatory role of PPP3CC in the IP3-Ca2+ signaling pathway. 展开 关键词: INOSITOL 1 5-TRISPHOSPHATE KAWASAKI-DISEASE SCHIZOPHRENIA SUSCEPTIBILITY ACTIVATION CA2 TRISPHOSPHATE EXPRESSION DOI: ...
PPP3CC feedback regulates IP3-Ca2+ pathway through preventing ITPKC degradation. ITPKC, a susceptibility gene of Kawasaki disease Pu,Li,Peng,... - 《Frontiers in Bioscience A Journal & Virtual Library》 被引量: 0发表: 2013年 PPP3CC feedback regulates IP3-Ca2+ pathway through preventing ITPKC ...
distinct Ca2+-release pathway activated by NAADP (Nicotinic ADP-ribose), Sphingosine and a distinct Ca2+-release pathway activated by NAADP (Nicotinic Acid Adenine Dinucleotide Phosphate). Within Ca2+-storing organelles, Ca2+ ions ...
In addition there are RyR-like channels activated by cADPR (cyclic ADP-ribose), Sphingosine and a distinct Ca2+-release pathway activated by NAADP (Nicotinic Acid Adenine Dinucleotide Phosphate). Within Ca2+-storing organelles, Ca2+ ions are bound to specialized Ca2+-buffering proteins. These ...
IP3通路可以引起细胞内肌浆网和内质网钙库Ca2+通过钙池操纵的钙通道流入细胞质,从而改变细胞内的Ca2+浓度[6],IP3通路改变细胞内的Ca2+浓度可以引起一系列的生物学效应。目前有关IP3通路的研究主要集中在肌肉、血管和心脏上,在脂肪代谢上的研究很少。为此,本研究用IP3通路的激动剂(去甲肾上腺素(NE))和抑制剂(肝素...
Vagal immune-to-brain communication: a visceral chemosensory pathway The immune system operates as a diffuse sensory system, detecting the presence of specific chemical constituents associated with dangerous micro-organisms,... Lisa,E.,Goehler,... - 《Autonomic Neuroscience》 被引量: 733发表: 2000...
This study demonstrated that the nuclear PLSCR1 facilitates the PLSCR1-IP3R1-Ca2+ pathway leading to the differentiation of primary AML cells (Figure 7), which is responsible for wogonoside-induced anti-leukemia activity, suggesting the potential of developing of wogonoside into a novel agent for...
细胞信号通路ppt细胞信号通路大全上下细胞信号通路ppt ip3_pathway.ppt,GP C R C N IP3 Pathway C D 1 9 Ag Iga Iga I gb I gb L A T TCR-CD3 Complex Growth Factor Receptor CaCn Complex MEF2 p300 CREB CBP Growth Factors Gene Expression NFAT I P 3 R Ca2+ Ga Gb Gg
However, MCU-dependent mitochondrial sequestration of Ca2+ entering through the SOCE pathway was essential to prevent slow deactivation of SOCE. Our findings show a stimulus-specific contribution of mitochondrial Ca2+ uptake to the SOCE machinery, likely through a role in shaping cytosolic Ca2+ micro...