Interleukin-1 Family Signaling Related to Agitation in Severe Mental DisordersGabriela HjellAttila SzaboLynn Mrch-JohnsenRené HolstNatalia TesliChristina BellThomas Fisher-VielerMaren Caroline Frogner WernerSynve Hoffart LundingMonica Ormerod
3) of the immune response and during the effector phase, as potential Signal 4s associated with tissue specific signaling and homing, driving either inflammation or healing and the fibroblastic response, mediated by IL-I尾 during the effector phase of the immune response as Signal 5s (1,2) ....
Interleukin-1 Receptor and Toll-Like Receptor Signaling The Toll-like receptor (TLR) family, consisting of 10 human members, recognize pathogen-associated molecular patterns, such as LPS and flagellin, and are components of the innate immune system. The interleukin-1 receptor (IL-1R) family recogn...
IL-1 (interleukin 1) receptor belongs to the Toll-IL-1-receptor (TIR) superfamily, which is defined by an intracellular TIR domain that initiates the signaling cascade. TIR receptors can be divided into 2 subgroups regarding the extracellular domains. One group contains a leucine-rich repeat mot...
Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway. Mol. Cell. ... G Takaesu,J Ninomiya-Tsuji,S Kishida,... - 《Molecular & Cellular Biology》 被引量: 436发表: 2001年 Interleukin-1 beta protects neur...
2.Dinarello CA. The interleukin-1 family: 10 years of discovery. FASEB J. 1994 Dec;8(15):1314-25. 3.Brikos C, Wait R, Begum S, O'Neill LA, Saklatvala J. Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding...
The IL-1 family of cytokines and receptors in rheumatic diseases Article 12 September 2019 IL-17 receptor–based signaling and implications for disease Article 19 November 2019 Shared inflammatory pathways of rheumatoid arthritis and atherosclerotic cardiovascular disease Article 25 May 2023 Refere...
Investigators have studied how production of the different members of the IL-1 family is controlled, the various biological activities of IL-1, the distinct and various functions of the IL-1 receptor (IL-1R) family and the complexity of intracellular signaling. Mice deficient in IL-1, IL-1 ...
These studies provide further evidence for the role of reduced interleukin-1α signaling in the decline of permeability barrier function in aged skin, and point to the potential use of cytokine augmentation in barrier dysfunction of the aged. 展开 关键词: epidermis aging interleukin-1 imiquimod ...
Biologic basis of serotonin reuptake inhibitor antidepressant-associated female sexual dysfunction: A novel signaling perspective Depression, which affects women twice as often as it does men, is rapidly becoming the second major cause of disability worldwide. This is true despite evi... HG Nurnberg ...