Immunity-Related Gtpase Family, Cinema 来源宿主 兔 反应性 人,小鼠,大鼠 保存建议 建议收到该Interferon-Inducible GTPase 5 (IRGC) Antibody产品后,储存温度为-20°C。避免重复冻融 其他 Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域...
Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity. J. Interferon Cytokine Res. 31, 79–87 (2011). Article CAS PubMed Google Scholar Mordstein, M. et al. Interferon-λ contributes to innate immunity of mice against influenza A virus but not against ...
immunity-related GTPase; ISG15, IFN-stimulated gene 15 kDa protein; MX1, myxovirus resistance 1; NOS2, nitric oxide synthase 2; NRAMP1, natural resistance-associated macrophage protein 1; OAS, 2ʹ-5ʹ oligoadenylate synthase; PKR, IFN-induced, RNA-activated protein kinase.*Other NADPH...
Our previous studies using differential mRNA display have shown that interferon-纬-inducible GTPase (IGTP), was up-regulated in coxsackievirus B3 (CVB3)-infected mouse hearts. In order to explore the effect of IGTP expression on CVB3-induced pathogenesis, we have established a doxycycline-inducible...
a pattern of evolution that is still actively continuing in several of the subfamilies. the structure of p47 gtpase genes and their splicing patterns the open reading frame of irg genes is typically encoded on a single long 3' exon (figure 2a ) behind one or more 5'-untranslated exons. ...
Gene targeting studies have distinguished four main effector pathways of the IFN-mediated antiviral response: the Mx GTPase pathway, the 2',5'-oligoadenylate-synthetase-directed ribonuclease L pathway, the protein kinase R pathway and the ISG15 ubiquitin-like pathway. As discussed in this Review, ...
We identified one of these genes as that encoding interferon (IFN)-inducible guanylate-binding protein 1 (or GBP1), which possesses GTPase activity. Analysis of endometrial biopsies by Northern blotting and RT-PCR demonstrated that GBP1 mRNA is specifically induced at the midsecretory phase of ...
The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation. J Biol Chem. 2002;277(8):6080–7. Article CAS PubMed Google Scholar Cheng YS, Colonno RJ, Yin FH. Interferon induction of fibroblast proteins with guanylate binding activity. J Biol ...
A signalling protein that binds guanine nucleotides. A GTPase is active in the GTP-bound state and is inactivated when it hydrolyses GTP into GDP. RNaseL (Ribonuclease L). A constitutively expressed, latent, nonspecific endoribonuclease that is activated by 2′,5′-oligoadenylate. Type I interfer...
Gate-16 but not LC3b specifically associated with the small GTPase ADP-ribosylation factor 1 (Arf1) to mediate uniform distribution of interferon-inducible GTPases. The lack of GABARAPs reduced Arf1 activation, which led to formation of interferon-inducible GTPase-containing aggregates and hampered...