InflammationCancerImmunityThe human immunity-related GTPase M (IRGM) is a GTP-binding protein that regulates selective autophagy including xenophagy and mitophagy. IRGM impacts autophagy by (1) affecting mitochondrial fusion and fission, (2) promoting the co-assembly of ULK1 and Beclin 1, (3) ...
2 The abbreviations used are: IRG immunity-related GTPase GBP guanylate-binding protein TUBE 1 tandem ubiquitin binding entity 1 MEF mouse embryonic fibroblast GMS glycine-methionine-serine GKS glycine-lysine-serine 3T3 3-day transfer, inoculum 3×105 cells. ...
GM4951 contains an interferon inducible GTPase (IIGP) domain, which is a Pfam28domain (#PF05049) built on 6 seed sequences of IRG protein family (TGTP1, IRGA6, IFI47, IRGM1, IGTP, IRGM2) for alignment. Considering the predominant expression of GM4951 in hepatocytes, we treated mouse ...
immunity-related GTPase family M protein) IRGM A gene on chromosome 5q33.1 that encodes immunity-related GTPase family member M (interferon-inducible protein 1), a putative GTPase required for clearing acute protozoan and bacterial infections. IRGM is thought to play a role in the innate immune ...
世联博研公司现货供应abbexa品牌订货号为Catalogue No: abx448008的Immunity-Related GTPase Family M Protein (IRGM) Antibody (FITC)产品
世联博研公司现货供应abbexa品牌订货号为Catalogue No: abx448003的Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 680)产品
CAS号: 英文名: Recombinant Human Immunity-Related GTPase Family, M 英文别名: Recombinant Human Immunity-Related GTPase Family, M 中文名: 中文别名: CBNumber: CB05753857 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 8 Recombinant Human Immunity-Related GTPase ...
Immunity-related GTPase family M (IRGM) is a human protein highlighted for its contribution to autophagy upon inflammation and infections. Studies have shown that IRGM is involved in the development of several cancers. In the current study, we investigated expression of IRGM and gastric cancer. ...
IFN-γp47 immunity-related GTPasephagosome acidificationInterferon-gamma IFN-γ)–induced remodeling of the bacterial phagosome for pathogen clearance elicits the aid of a new family of GTPases termed the p47 IRGs. Members of this group reside primarily on......
RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival. Cell 2006; 127:157- 170. 74 Camonis JH, White MA. Ral GTPases: corrupting the exocyst in cancer cells. Trends Cell Biol 2005; 15:327-332. 75 Hamad NM, Elconin JH...