Integrin and cell adhesion molecules. Microscopy. 757:297-323.M. (ed.) Shimaoka, W. Fu, and B.-H. Luo. "Integrin and cell adhesion molecules: Methods and protocols". In: Methods in molecular biology 757 (2011), pp. 81-99.Chigaev A, Sklar LA. Integrin and Cell Adhesion Molecules....
These include: 1) the integrins, heterodimeric molecules that function both as cell-substratum and cell-cell adhesion receptors; 2) the adhesion molecules of the immunoglobulin superfamily, which are involved in cell-cell adhesion and especially important during embryo-genesis, wound healing, and the...
aCell adhesion molecules integrin αV can influence the radiosensitivity of human nasopharyngeal carcinoma CNE-2Z cells and the inhibition of cell apoptosis might be its mechanism, proved by three dimensional culture model to mimic solid tumor in vivo. 细胞粘着分子integrin αV可能影响人的鼻咽癌CNE-...
Cell adhesion is the fundamental process in tissue development by which cells form contacts with each other or with their substratum through specialized protein complexes. Although cells express various cellular adhesion molecules (such as cadherins, members of the immunoglobulin superfamily, syndecans, i...
Beta.sub.2 integrin cell adhesion molecule inhibitors the present invention concerns compositions and methods for blocking or modulating the function of the Beta.sub.2 Integrin family of cell adhesion molecules... MS Perez 被引量: 0发表: 1999年 Determining...
Integrin-mediated cell adhesion: the cytoskeletal connection. Members of the integrin family of cell adhesion molecules play a pivotal role in the interaction between animal cells and the extracellular matrix. This ar... DR Critchley,MR Holt,ST Barry,... - 《Biochem Soc Symp》 被引量: 572发表...
Cell Adhesion MoleculesIntegrin alpha3beta1Growth factors, integrins, and the extracellular matrix (ECM) are known to play key roles in epidermal wound ... MM Santoro,G Gaudino,PC Marchisio - 《Developmental Cell》 被引量: 416发表: 2003年 The UNC-112 Gene in Caenorhabditis elegansEncodes a No...
背景资料Integrin αM(CD11b) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin ∫2 to...
28 Currently, there are approximately 90 kinds of integrin-targeting therapies in clinical trials, including integrin antagonists and imaging agents, including small molecules, antibodies, synthetic mimic peptides, antibody–drug conjugates (ADCs), CAR T-cell therapy, imaging agents, etc. A serious ...
Binding of the DATK32 monoclonal antibody has been shown to induce aggregation of the CD8+ T cell lymphoma TK1, and block LPAM-1-mediated cell adhesion.Applications Reported: This DATK32 (DATK-32) antibody has been reported for use in flow cytometric analysis.Appl...