CellAdhesionMoleculesCervixNeoplasms钙粘着糖蛋白类Integrin and E-cadherin cell adhesion molecules are important in the maintenance of normal epithelial structures, and altered expression of these molecules may be important in epithelial tumors, particularly in the processes of invasion and metastasis. This ...
Adhesion receptors include integrins, the immunoglobulin superfamily, cadherins, cellular adhesion molecules (CAMs), and homing receptors.1 Among all the cell adhesion receptors, integrins are important for “maintaining the integrity of the cytoskeletal-ECM linkage,” as established in the 1970's and...
Cell adhesion is the fundamental process in tissue development by which cells form contacts with each other or with their substratum through specialized protein complexes. Although cells express various cellular adhesion molecules (such as cadherins, members of the immunoglobulin superfamily, syndecans, i...
(VLA) subfamily of adhesion molecules. Integrin heterodimers containing CD29 are involved in cell-cell and cell-matrix adhesion. CD29 is expressed broadly on lymphocytes and monocytes, with lower levels of expression on granulocytes. The TS2/16 antibody has been found to possess...
Malignant transformation of melanocytes frequently coincides with an alteration in the expression of cell–cell adhesion molecules (cadherins) and cell-extracellular matrix proteins (integrins). How these two adhesion systems interplay to impact on cell invasion remains to be described in melanoma. Method...
Integrins, as important transduction molecules, mediate a variety of biophysical stimuli to regulate bone metabolism. By mediating cell-ECM activity, integrins have become important target therapy strategies for bone metabolism-related diseases and the incubator for drug delivery system development. ...
Adhesion Molecules in Angiogenesis Adhesion Molecules on VSMC Adhesive Interactions in Allergy and Asthma Adipose-derived Stem Cell Markers Airway Inflammation and Remodeling B Cell Chemotaxis, Migration, and Adhesion Basophils Co-stimulatory and Co-inhibitory Molecule...
Binding of the DATK32 monoclonal antibody has been shown to induce aggregation of the CD8+ T cell lymphoma TK1, and block LPAM-1-mediated cell adhesion.Applications Reported: This DATK32 (DATK-32) antibody has been reported for use in flow cytometric analysis.Applic...
背景资料Integrin αM(CD11b) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin ∫2 to...
Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands, such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), ...