cell adhesionfibronectinintegrinmechanosensingtalinIntegrins are heterodimeric cell surface receptors ensuring the mechanical connection between cells and the extracellular matrix. In addition to the anchorage of cells to the extracellular matrix, these receptors have critical functions in intracellular signaling,...
Morgan, M. R., Humphries, M. J. and Bass, M. D. (2007). Synergistic control of cell adhesion by integrins and syndecans. Nat. Rev. Mol. Cell Biol. 8, 957-969.Synergistic control of cell adhesion by integrins and syndecans - Morgan, Humphries, et al. - 2007 () Citation Context...
D. Synergistic control of cell adhesion by integrins and syndecans. Nature Rev. Mol. Cell Biol. 8, 957–969 (2007). Article CAS Google Scholar Download references Acknowledgements The authors are grateful to K. Yamada for providing the photographs for FIG. 1 and to B. Morgenstern for ...
Cell adhesion: How integrins are activated. Nature, 390, 15-17.Lasky, " How Integrins Are Activated, " Nature, 390(6655):15, 17 (1997).Lasky LA. How integrins are activated. Nature 390: 15; 17, 1997.Lasky LA. How integrins are activated. Nature 390: 15, 17, 1997....
Integrins in cell adhesion and signaling. 来自 NCBI 喜欢 0 阅读量: 106 作者: SK Akiyama 摘要: Cell adhesive interactions play important roles during many normal physiological processes such as embryonic development and wound repair, and also during the progression of diseases such as cancer. Cell ...
Integrin adhesion complexes form in both tissues, and are thought to carry out a variety of functions. In particular, integrins mediate attachment between the AS and the underlying yolk cell through adhesion to a layer of laminin-rich ECM; disruption of laminin phenocopies loss of integrin ...
The meaning of CELL ADHESION MOLECULE is any of various molecules (such as cadherins, integrins, and selectins) on the surface of a cell that bring about adhesion by binding to molecules on the surface of other cells or on extracellular material —abbrev
Integrin cell adhesion is mediated by proteins generated by epithelial cells in the extracellular matrix known as thebasal lamina. Integrins use adaptor proteins like plectins and BP230 to attach the extracellular matrix to keratin intermediate filaments. ...
A hallmark of integrins is that ligand binding requires an integrin-activation step that is induced by the cytoplasmic adaptor proteins talin and kindlin22,23,24,25,26,27,28. Disruption of talin or kindlin binding to integrins induces rapid FA disassembly and curbs cell-substrate adhesion, ...
Focal adhesion Integrins Mechanotransduction Tight junctions Latest Research and Reviews Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosis Su, Zhao, Jiang and colleagues identify IGFBP6 as an intrinsic downregulator of the inflammatory response lost in disturbed flow-induced atherosclerotic ...