EC 1.1.1.205; IMDH2; IMP (inosine 5'-monophosphate) dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; IMP Dehydrogenase 2; IMP Oxireductase 2; IMPD 2; IMPD2; IMPD2IMP oxireductase 2; IMPDH 2; IMPDH2; IMPDH-II; inosine 5' phosphate dehydrogenase 2; inosine mono...
Mycophenolic acid (MPA) is a selective inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH), the rate-limiting enzyme of de novo synthesis of guanine nucleotides. The isoenzyme IMPDH2 predominates in activated lymphocytes, and its inhibition by MPA is part of standard immunosuppressive regimens...
Hedstrom, Kinetic mechanism of human inosine 5'- monophosphate dehydrogenase type II: random addition of substrates and ordered release of products. Biochemistry, 1997. 36(28): p. 8479-83.Wang, W.; Hedstrom, L. Kinetic mechanism of human inosine 50- monophosphate dehydrogenase type II: random...
中文名称:Recombinant Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) 英文名称:Recombinant Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) CAS号: 分子式: 分子量:0 EINECS号: Mol文件:Mol File Recombinant Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2)供应商 更多 上海...
Inosine 5′-monophosphate (IMP) is used as a substrate to study the distribution, specificity and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH). 名称和识别符 安全和危险性(GHS) 质检证书(COA) 相关文档 此产品的引用文献(2)
Inosine 5-monophosphate dehydrogenase (IMPDH; EC 1:肌苷5单核苷酸脱氢酶(IMPDH;EC 1.doc,CONTENTS Abstract pag. 3 CHAPTER 1. Introduction 6 1.1. Cancer Chemotherapy 7 1.2. Nucleoside and Nucleotide Analogues 9 1.2.1. Mechanism of Action 9 1.2.2. Purine N
常用英文名:Uridine monophosphate CAS号:58-97-9 分子式:C9H13N2O9P 分子量:324.181 产地:西安 规格:1mg 5mg 10mg 纯度:99% 用途:仅用于科研 温馨提示:仅用于科研,不能用于人体实验! 单磷酸腺苷(英文:Adenosine monophosphate,简称AMP),又名一磷酸腺苷,5'-腺嘌呤核苷酸或腺苷酸,是一种在核糖核酸(RNA)中发现...
(15)584.1.3.ConformationalAnalysis614.1.4.BiologicalEvaluation62CHAPTER5.RibonucleotideReductaseasTargetforAntitumorAgents635.1.RoleofRibonucleotideReductaseinthesynthesisofDNA645.2.MechanismofCatalysisofRR665.3.CristalStructureofRR685.4.RibonucleotideReductaseInhibitors705.4.1.TranslationInhibitors705.4.2.Dimerisation...
Inosine monophosphate dehydrogenase 2 (IMPDH2) is a constitutively expressed enzyme responsible for the rate-limiting step in guanine synthesis with homologues in all forms of life. We are becoming increasingly aware that many metabolic enzymes, including IMPDH2, form inducible large-scale assemblies as...
Design, synthesis and biological evaluation of human inosine 5'-monophosphate dehydrogenase inhibitors: 1,5-diazabicyclo(3.1.0)hexane-2,4-diones, as novel ... IMP dehydrogenase (IMPDH, EC 1.1.1.205) controls a critical junction in the metabolism of purine nucleotides. IMPDH catalyzes the formatio...