doi:WO2005039552 A2CHO AesopKIRSCHBERG Thorsten A.WATKINS William J.FARDIS MariaCHONG Lee S.CAWO2005039552A2 Oct 25, 2004 May 6, 2005 Aesop Cho Inosine monophosphate dehydrogenase inhibitors as phosphonate derivatives
C Legendre, E Thervet - Modern Immunosuppressives, 2001 - link.springer.com Although most of the clinical experience of MMF accumulated over the past years concerns organtransplantation, there is growing evidence that this drug might be indicated Only one patientexperienced steroid-responsive acute ...
英文别名: Human Inosine-5’-Monophosphate Dehydrogenase (IMPDH) Inhibitor Screening Assay Kit中文名: 中文别名: CBNumber: CB79717094 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 Human Inosine-5’-Monophosphate Dehydrogenase (IMPDH) Inhibitor Screening Assay Kit化学性质...
Synthesis of the inosine 5'-monophosphate dehydrogenase (IMPDH) Inhibitors, J. EnzymeG. Cholewinski, D. Iwaszkiewicz-Grzes, M. Prejs, A. Głowacka, K. Dzierzbicka, Synthesis of the inosine 50-monophosphate dehydrogenase (IMPDH) in- hibitors, J. Enzyme Inhib. Med. Chem. 30 (2015) ...
Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design. Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-indepen... ...
Inosine monophosphate dehydrogenase activity in renal allograft recipients during mycophenolate treatment. Scand J Clin Lab Invest 2006;66:31- 44.VETHE N T; MANDLA R; LINE P D;.Inosine monophosphate dehydrogenase activity in renal allograft recipients during mycophenolate treatment.Scand J Clin Lab ...
The thermodynamic properties of binding of the substrate, inosine monophosphate (IMP), and the uncompetitive inhibitor, mycophenolic acid, to inosine monophosphate dehydrogenase (IMPDH) were measured. Specifically, the free energy, entha... Frank,J.,Bruzzese,... - 《Biochemistry》 被引量: 94发表:...
Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway. Inosine monophosphate dehydrogenase (IMPDH) is a rate-limiting enzyme required for the de novo synthesis of guanine nucleotides from IMP. VX-944 (...
Inosine 5-monophosphate dehydrogenase (IMPDH; EC 1:肌苷5单核苷酸脱氢酶(IMPDH;EC 1.doc,CONTENTS Abstract pag. 3 CHAPTER 1. Introduction 6 1.1. Cancer Chemotherapy 7 1.2. Nucleoside and Nucleotide Analogues 9 1.2.1. Mechanism of Action 9 1.2.2. Purine N
aInosine monophosphate dehydrogenase (IMPDH) is a key rate limiting enzyme that is required for de novo guanosine production for incorporation into DNA, RNA, or glycoproteins. 肌甙一磷酸盐脱氢酶 (IMPDH) 是限制为de novo鸟苷生产需要为并网入脱氧核糖核酸、RNA或者糖蛋白的酵素的关键利率。 [translate]...