Thus, although it is clear that the byproducts of normal energy metabolism can cause DNA damage, and that DNA damage can impact cellular energy metabolism, whether and how DNA damage itself exerts feedback control over energy metabolism is poorly characterized, particularly on the organismal level....
valuable chemical intermediate. Efficient capture of CO2into 3-HP can improve the carbon yield in its production, and this step is also crucial in the native CO2fixation pathway 3-hydroxypropionate/4-hydroxybutyrate (HP/HB) cycle10and 3-hydroxypropionate bi-cycle11. 3-HP holds a significant posit...
Weight loss is proportional to increases in fasting serum beta-hydroxybutyrate concentrations in adults with severe obesity undergoing a meal replacement programme Human Nutrition & Metabolism, Volume 32, 2023, Article 200192 Francis Martin Finucane,…, Martin O'Donnell View PDFShow 3 more articles Art...
the precursor to both leucine and valine. AHAS also drives the conversion of 2-oxobutyrate to acetohydroxybutyrate, the precursor to isoleucine. Because AHAS has a substrate preference for
Alexandre; Buffet Delphine; Vezzosi Jean Christophe;.Increased plasma 13-hydroxybutyrate levels during the fasting test in patients with endogenous hyperinsulinaemic hypoglycaemia.European Federation of Endocrine So- cieties.2013.91-Buffet A, Vezzosi D, Maiza JC, Grunenwald S, Bennet A, Caron P. ...
coli ribosome binding site and a trc strong promoter (pSJS1) to obtain poly-#beta#-hydroxybutyrate (PHB) with long chain length. When the inducer, IPTG was added to the culture at 0.4 mM, the average molecular weight was 1.1 X 10~6 Da. However, an even greater increase of the PHB ...
POLY-beta-hydroxybutyrateBIOMASS productionSYNECHOCYSTISGENETIC overexpressionGENESGLYCOGENThe overexpression of the RuBisCO (rbc) gene has recently become an achievable strategy for increasing cyanobacterial biomass and overcoming the biocompound production restriction. We successfully constructed two rbc-...
Increased lactate/pyruvate ratio with normal beta- hydroxybutyrate/acetoacetate ratio and lack of oxygen supply dependency in a patient with fatal septic shock. Intensive Care Med 1997;23:114-116.Gallet D, Goudable J, Vedrinne JM, Viale JP, Annat G (1997) Increased lactate/pyruvate...
In babies given an equicaloric amount of breast-milk, glucose rose, if a certain level of betahydroxybutyrate was present in plasma as indicator of endogenous fat oxidation. The rate of gluconeogenesis seemd to be dependent on oxidation of fatty acids and on availability of substrates. These ...
In addition, dissociated VMN neurons from DIO and DR rats were equally sensitive to the largely excitatory effects of beta-hydroxybutyrate. Thus while DR rats respond to increased VMH ketone levels by decreasing their intake after 3 days of HE diet, this is not the case of DIO rats. These ...