Among them, only beta-hydroxybutyrate (BHB) was elevated in CRC. Here, we first confirm the increased level of beta-hydroxybutyrate by targeted metabolomic analysis using an independent cohort of 400 serum samples by UPLC-QQQ-MS/MS analysis. Using appropriate cell and animal models, we find ...
We found elevated levels of betahydroxybutyrate (BHB) in serum and whole-blood (WB) of prolactinomas (0.481±0.211/0.329±0.228mM in serum/WB), but it was statistically significant (p≤0.0033, Bonferroni correction) only in serum when compared with LH/FSH-secreting tumor patients (0.269±0.139...
Elevated Serum Beta-Hydroxybutyrate Levels (B-hb) in Patients with Type 2 Diabetes Mellitus Using Sodium-Glucose Cotransporter 2 (SGLT-2) InhibitorSimant Thapa
Figure 9. Alterations in CREBp-1, AMPK protein (a), metabolic intermediates beta-hydroxybutyrate (b) and acetoacetate (c) levels in vehicle control, NLCs-KAA, NLCs-PUNI-KAA and PUNI and orlistat treated maturing adipocyte after 14 days. Each of the values are means ± SD (n = 6). Sign...