Immune function of microgliaHans LassmannHartmut WekerleWilliam F. HickeyJack Antel
Immune function of microglia 来自 万方 喜欢 0 阅读量: 126 作者: F Aloisi 摘要: During the past decade, mechanisms involved in the immune surveillance of the central nervous system (CNS) have moved to the forefront of neuropathological research mainly because of the recognition that most ...
The aim of this review is to address the immune function of both glial cells and neurons, and the roles they play in regulating inflammatory processes and maintaining homeostasis of the CNS. 展开 关键词: Microglia astrocyte neuron neuroinflammation innate immunity adaptive immunity ...
They fight invaders, clear debris and tend neural connections, but sometimes microglia go rogue. Preventing this malfunction may offer new treatments for brain conditions including Alzheimer's
Together with references 110 and 111, this study showed that microglia can be defined by a specific molecular signature in mice. CAS PubMed Google Scholar Greenhalgh, A. D. et al. Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury. PLOS Biol. ...
Microglia, resident macrophages of the brain, function as immune effector and accessory cells. Paradoxically, they not only play a role in host defense and... GA Cabral,F Marcianocabral - Paragon House, 被引量: 241发表: 2005年 Immune regulation within the central nervous system The brain const...
The use of TMS has been reported to encourage microglia to cease overactivity, and return to healthier function. This is possible because these cells are responsive to brainwaves, a type of electromagnetism [1]. Applying magnetic stimulation may help break a cycle of stress, giving the brain (...
To investigate the mechanism of Golgi matrix protein 130(GM130) regulating the antiviral immune response of TLR3 after herpes simplex virus type 1(HSV-1) infection of microglia cells. We explored the regulatory effects of berberine on the immune response
Host microbiota constantly control maturation and function of microglia in the CNS. Nat. Neurosci. 18, 965–977 (2015). CAS PubMed PubMed Central Google Scholar Sampson, T. R. et al. Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson’s disease. Cell 167,...
Phagocytosis is an important physiological function of microglia, as clearance of dead cells or dangerous debris is crucial to the maintenance of brain functions and sustained phagocytic activity is typical for M2 macrophages and microglia [31], [32]. Other microglial functions, such as basal ...