Since light microscopy does not permit the observation of the chromatin fibre, DIA was performed on digitalized images of metaphase chromosomes under electron microscopy. The application of a LUT (Look Up Table) within the DIA software assigns a colour to each grey level of a digital image. The...
The next example targets cytogenetic images of human metaphase cells. This is a classical application of area opening. The task is to preprocess the image by segmenting out the chromosomes from the nuclei, stain debris, and the background. Fig. 6.8 shows the input image (a), the thresholded...
The term 'chromosome analysis' covers a range of quite distinct problems which have little in common beyond requiring measurements of images of chromosomes at or near to the metaphase of cell division. The most common task (and what most people understand by chromosome analysis) is to detect ...
Automatic metaphase analysis of Chinese hamster cells with a chromosome image analyzing systemMOUSE SPLENOCYTE ASSAYBIOLOGICAL MONITORINGX-RAYSFISSION NEUTRONSBLEOMYCINA modified mouse splenocyte culture system was standardized after testing different mitogens (i.e., phytohemagglutinin (PHA), concanavalin ...
For example, a time study of karyotyping of chromosomes showed that the time required for picking up a metaphase cell and taking its photograph and the time required for karyotyping itself were about the same. Hence no automatic system for processing microscopical images will become practical unless...
DaCSeg: Divide and conquer for accurate overlapping chromosome instance segmentation in metaphase cell images. Biomed. Signal Process. Control 2024, 89, 105880. [Google Scholar] [CrossRef] Cui, Z.; Yao, J.; Zeng, L.; Yang, J.; Liu, W.; Wang, X. LKCell: Efficient Cell Nuclei ...